应用PDCA循环干预我院PCI患者围术期预防用抗菌药物的效果分析

目的:探讨PDCA循环对经皮冠状动脉介入治疗(PCI)患者围术期预防用抗菌药物的干预效果。方法:应用PDCA循环对我院PCI围术期预防用抗菌药物作持续性干预。将干预前随机抽查的PCI病例作为对照组,第一阶段干预后抽查的PCI病例作为干预1组,第二阶段干预后抽查的PCI病例作为干预2组,将3组预防用抗菌药物使用情况进行比较分析。结果:与对照组相比,干预后我院PCI围术期预防用抗菌药物使用率由97.50%分别下降至7.50%、1.00%,具有显著性差异(P<0.01);干预1组和干预2组平均抗菌药物费用及抗菌药物费用占总药品费用的百分比均明显下降,而术后感染发生率并未增加。结论:PDCA循环能够促进PCI围术期预防用抗菌药物的合理性,建议在抗菌药物的管理中推广应用PDCA循环,以促进临床合理用药。

Analysis of Intervention Effect of PDCA on Antibiotics for Prophylactic Use in PCI Patients of Our Hospital

OBJECTIVE： To investigate the intervention effect of PDCA on perioperative prophylactic application of antibiotics in percutaneous coronary intervention （PCI） patients of our hospital. METHODS： PDCA was applied for continuous intervention to perioperative prophylactic application of antibiotics in PCI patients of our hospital. PCI cases were randomly sampled before inter- vention as control group. PCI cases were sampled after first stage of intervention as intervention group 1; and were sampled after second stage of intervention as intervention group 2. The prophylactic application of antibiotics were analyzed and compared among 3 groups. RESULTS： Compared with control group, the utilization ratio of antibiotics for perioperative prophylactic use decreased from 97.50% to 7.50% and 1.00%, respectively; there was significant difference （P〈0.01）. Average antibiotics cost and ratio of antibiotics cost to drug cost decreased significantly in intervention groups; while the incidence of postoperative infection had no change after intervention. CONCLUSIONS： PDCA can promote rational use of antibiotics for prophylactic use in PCI patients. It is suggested to use PDCA in the management of antibiotics to promote clinical rational drug use.