Kanematsu Research Laboratories, Royal Prince Alfred Hospital, Missendon Road, Camperdown, Australia.
Abstract:
This report documents one patient with myelodysplasia evolving into acute leukemia who showed a t(Y;1) translocation confirmed by in situ hybridization. Most of the q arm of the Y chromosome was translocated to an additional q arm of chromosome 1, resulting in trisomy 1q. To our knowledge only four other cases with this t(Y;1) have been reported.