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针刺对肾性高血压大鼠6-酮-前列腺素F1及血栓素B2影响的研究
引用本文:刘丹,樊爽,慈玉莹.针刺对肾性高血压大鼠6-酮-前列腺素F1及血栓素B2影响的研究[J].针灸临床杂志,2003,19(8):69-70.
作者姓名:刘丹  樊爽  慈玉莹
作者单位:1. 黑龙江中医药大学附属一院,黑龙江,哈尔滨,150040
2. 黑龙江中医药大学2000级博士,黑龙江,哈尔滨,150040
摘    要:目的:探讨针刺治疗高血压的机理。方法:选用大鼠制备肾性高血压模型,以传统针刺治疗,观察了针刺对肾性高血压大鼠的血压、6-酮-前列腺素Fl(6-Keto-PGF1)、血栓素B2(TXB2)及6-Keto-PGF1/TXB2的影响。结果:针刺能够明显降低肾血管性高血压大鼠的血压并能明显升高6-Keto-PGF1左血浆中的含量及6-Keto-PGFl/TXB2比值。结论:针刺能增加6-Keto-PGF1的含量及它与TXB2的比值,以达到持续而稳定的降压效果。

关 键 词:肾性高血压  针刺疗法  大鼠  6-酮-前列腺素F1  血栓素B2
文章编号:1005-0779(2003)08-0069-02
修稿时间:2003年4月2日

The study on 6-keto-PGF1 and TXB2 of renovascular hypertension rats treated with acupuncture
LIU Dan,FAN Shuang,CI Yv-ying Author's address:Affiliated first hospital to Heilongjiang university of TCM,Harbin ,China.The study on 6-keto-PGF1 and TXB2 of renovascular hypertension rats treated with acupuncture[J].Journal of Clinical Acupuncture and Moxibustion,2003,19(8):69-70.
Authors:LIU Dan  FAN Shuang  CI Yv-ying Author's address:Affiliated first hospital to Heilongjiang university of TCM  Harbin  China
Institution:LIU Dan,FAN Shuang,CI Yv-ying Author's address:Affiliated first hospital to Heilongjiang university of TCM,Harbin 150040,China
Abstract:Objective:To discuss the mechanism of treating hypertension with acupuncture.Methods:Established the animal models in rats by the stenosis of bilateral renal arteries and applied traditional acupuncture treatment.Observed its effect on the blood pressure,6-Keto-PGF 1,TXB 2 in arterial plasma in rats and 6-Keto-PGF 1/TXB 2.Results:Acupuncture can significantly reduce the blood pressure in rats and effectively increase 6-Keto-PGF 1 and the ratio of 6-Keto-PGF 1 and TXB 2 to reach the aim of durable and stable effect on reducing the blood pressure.
Keywords:Acupuncture  Renovascular hypertension  6-Keto-PGF  1  TXB  2
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