A novel HLA-DRB1 allele, HLA-DRB1*0465, was identified in a Hodgkin's lymphoma cell line |
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Authors: | Witter K Mautner J Volgger A Zahn R Kauke T |
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Affiliation: | Laboratory of Immunogenetics, University Munich, Munich, Germany; Institute for Clinical and Molecular Biology, GSF-National Research Center for Environment and Health, Munich, Germany |
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Abstract: | The new human leucocyte antigen-DRB1*0465 allele was identified in the Hodgkin's lymphoma cell line KM-H2. This novel allele differs from the DRB1*0406 allele by a single nucleotide exchange at position 288 (211) (A→T), which results in an arginine to tryptophan amino acid replacement at codon 90 in the new allele. |
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Keywords: | human leucocyte antigen-DRB1*0465 Hodgkin's lymphoma sequence-based HLA-typing |
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