| 阿托伐他汀对急性脑梗死患者颈动脉粥样硬化斑块的影响 |
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| 引用本文： | 董秋艳,樊丽娟,白智华,张伟,陈瑨,权丽,李博,彭享胜.阿托伐他汀对急性脑梗死患者颈动脉粥样硬化斑块的影响[J].中国误诊学杂志,2010,10(28):6814-6815. |
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| 作者姓名： | 董秋艳 樊丽娟 白智华 张伟 陈瑨 权丽 李博 彭享胜 |
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| 作者单位： | 武警北京总队第二医院内三科,100037 |
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| 摘 要： | 目的探讨阿托伐他汀对急性脑梗死患者颈动脉粥样硬化斑块的影响及调脂作用。方法随机选择对照组及研究组各50例,所有病例均给予阿司匹林肠溶片基础上,研究组给予阿托伐他汀钙,观察两组治疗前后颈动脉内膜中层厚度（IMT）、胆固醇（TC）、甘油三脂（TG）、低密度脂蛋白（LDL-C）和高密度脂蛋白（HDL-C）。结果研究组1 a后IMT缩小显著（P〈0.05）,且TG、TC、LDL-C下降显著,HDL-C升高显著,P〈0.01。结论服用阿托伐他汀1 a可以稳定和减轻动脉粥样硬化斑块。
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| 关 键 词： | 脑梗塞/药物疗法 动脉硬化/药物疗法 颈动脉疾病/药物疗法 庚酸类/治疗应用 吡咯类/治疗应用 治疗结果 人类 |
Influence of Atorvastatin for Carotid Artery Arteriosclerosis Clot of Patients with Acute Cerebral Infarction |
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| Institution: | DONG Qiu-yan,FAN Li-juan,BAI Zhi-hua,et al.3rd Department of Medicine,2nd Hospital Affiliated to Headquarters of Armed Police Force of Beijing,Beijing 100037,China |
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| Abstract: | Objective To explore the influence for carotid artery arteriosclerosis clot and the regulative effects on serum lipids of patients with acute cerebral infarction.Methods To select the control group（n=50） and study group（n=50） randomly,the patients in study group received atorvastatin calcium based on all patients received aspirin enteric-coated tablets in two groups,then to observe IMT、TC、TG、LDL-C and HDL-C of them before and after therapy.Results After 1 year,IMT was obvious shorter（P0.05） and TG、TC、LDL-C were obvious lower and HDL-C was obvious higher（P0.01） in study group than control group.Conclusion Oral atorvastatin calcium for a year can stable and decrease carotid artery arteriosclerosis clot. |
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| Keywords: | Brain Infarction/drug therapy Arteriosclerosis/drug therapy Carotid Artery Diseases/drug therapy Heptanoic Acids/therapeutic use Pyrroles/therapeutic use Treatment Outcome Humans |
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