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中药系统的方法学——中药系统原理
引用本文:朱旭祥,朱沁未.中药系统的方法学——中药系统原理[J].世界科学技术,2001,3(1):16-19.
作者姓名:朱旭祥  朱沁未
作者单位:朱旭祥(浙江省医学科学院,杭州,310013)       朱沁未(浙江省医学科学院,杭州,310013)
摘    要:中药现代化的关键是自身庞大系统的方法学,即中药庞大数目的综合化学成分和复杂体系的整体药理作用的方法学,中药系统原理是处理中药庞大系统一般规律的方法学,中药系统原理以中药化学特征谱来表达综合活性成分,以基因组学和基因表达的细胞因子来揭示整体活性作用。

关 键 词:中药方法学  中药系统原理  中药化学  药效评价  配位化学  中药活性成分  中药现代化

Systematic Principle-Methodology of the System in Chinese Materia Medica
Zhu Xuxiang Zhu Qinwei.Systematic Principle-Methodology of the System in Chinese Materia Medica[J].World Science and Technology(Modernization of Traditional Chinese Medicine),2001,3(1):16-19.
Authors:Zhu Xuxiang Zhu Qinwei
Institution:Zhejiang Academy of Medical Sciences Hangzhou 310013
Abstract:The key of the modernization of the Chinese materia medica is the methodology of the enormous and complex system of the Chinese materia medica itself, that is the methodology of the comprehensive chemical constituents and the whole pharmacological effects of the system. The systematic principle in Chinese materia medica is just the methodology dealing with the general rules of the enormous and complex system. The core of the systematic principle is how to wxpress and obtain the quantitative and controllable comprehensive chemical active constituents in stead of a single compound, and how to evaluate the whole pharmacological effects of the comprehensive constituents instead of a single effect. The systematic principle in Chinese materia medica expresses the comprehensive active constituents with the chemical feature spectra of Chinese materia medica, and exposes the whole pharmacological effects of the comprehensive constituents with genomics and cytokine expressed by genes and genomes.
Keywords:Methodology of TCM  System  Principle  Coordination chemistry  Evaluation of the effectiveness of medicine  Active composition of TCM  
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