龙岩市1999～2002年流感监测结果分析

目的 :探索流感流行的规律 ,掌握流感流行信息 ,及时对疫点进行疫情调查 ,为制定防制方案提供科学依据。方法 :对门诊就诊的上感病例进行流行病学观察。用常规鸡胚双腔法分离流感病毒。以微量血凝抑制试验 (HI)法测定正常人群免疫水平。结果 :1999年及 2 0 0 0年未检出流感病毒 ,2 0 0 1年分离到 A1(H1N1)亚型流感病毒 12株 ,2 0 0 2年分离得B型 Victoria系流感病毒 2 8株与 A3(H3N2 )亚型流感病毒 2株。正常人群免疫水平 ,1999年阳性率以 A3(H3N2 )亚型阳性率最高 ,达 79.2 5 % (GMT 79.2 3) ;2 0 0 0年以 A1(H1N1)亚型最高 ,达 88.6 8% (GMT 6 4 .32 ) ;2 0 0 1年以 A1(H1N1)亚型最高 ,达 76 .4 0 % (GMT2 8.2 8) ;2 0 0 2年以 A1(H1N1)亚型阳性率最高 ,达 78.2 6 % (GMT15 .2 9)。两系B型流感中该市只有 Yam agata系在人群中有抗体 ,而 Victoria系抗体在低年龄组人群中未检出。结论 :该市 2 0 0 3年应重点加强防范 B型 Victoria系流感病毒株向乡镇流行以及 A3亚型流感病毒株可能引起的爆发或流行

ANALYSIS ON SURVEILLANCE RESULT OF INFLUENZA IN LONGYAN CITY FROM'1999 to 2002

Objective:To study the epidemical regulation of the influenza,to capture the epidemic information of the influenza,to investigate the epidemic situation in time,and to provide the scientific proof for establishing the system project for defending and preventing influenza effectively.Methods:To proceed the epidemiological observation with the clinic patients who take the upper-breather infection,vaccinate the embryonated chicken eggs' double cavity to isolate influenza virus and test the normal crowd's antibody level with microplate hemagglutination inhibition(HI) test.Results:No influenza virus was isolated in 1999 and 2000,but 12 strains of subtype A1(H1N1) influenza virus in 2001 and 28 strains of B type victoria series influenza virus and 2 strains of subtype A3(H3N2) influenza virus in 2002.The normal crowd's antibody level is that the highest positive rate of subtype A3(H3N2) was 79.25%(GMT 79.23)in 1999,and the highest positive rate of subtype A1(H1N1) was 88.68%(GMT 64.32)in 2000,and the highest positive rate of subtype A1(H1N1) was 76.40%(GMT 28.28)in 2001,and the highest positive rate of subtype A1(H1N1) was 79.25%(GMT 15.29)in 2002.Of the two series of B type influenza,only Yamagata series antibody appeared in the local crowd,Victoria series antibody almost weren't found in the local youngster.Conclusion:In 2003,we should enhance to defend the spread down the countryside of B type Victoria series influenza virus and the probability of outbreak or epidemic caused by subtype A3 influenza virus.