| 肾癌组织MMP-10和VEGF表达及其临床意义的研究 |
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| 引用本文： | 石结武,周林玉,谈宜傲,于靳,古爱军,宣强,孙友文.肾癌组织MMP-10和VEGF表达及其临床意义的研究[J].中华肿瘤防治杂志,2011,18(10):776-779. |
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| 作者姓名： | 石结武 周林玉 谈宜傲 于靳 古爱军 宣强 孙友文 |
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| 作者单位： | 安徽医科大学附属省立医院泌尿外科,安徽合肥,230001 |
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| 摘 要： | 目的:研究MMP-10和VEGF 在肾癌组织中的表达及其临床意义.方法:采用免疫组织化学技术SP法检测56例肾细胞癌(其中20例伴发淋巴结转移)及10例距癌旁＞2 cm正常肾组织的MMP-10和VEGF表达,并分析其与MVD等临床病理参数的关系.结果:56例肾细胞癌组织中MMP-10和VEGF的阳性表达率分别为66.1...
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| 关 键 词： | 肾肿瘤/病理学 癌 肾细胞/病理学 基质金属蛋白酶类 血管内皮生长因子A 免疫组织化学 |
Expression and clinical significance of MMP-10 and VEGF in renal cell carcinoma |
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| SHI Jie-wu,ZHOU Lin-yu,TAN Yi-ao,YU Jin,GUAi-jun,XUAN Qiang,SUN You-wen.Expression and clinical significance of MMP-10 and VEGF in renal cell carcinoma[J].Chinese Journal of Cancer Prevention and Treatment,2011,18(10):776-779. |
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| Authors: | SHI Jie-wu ZHOU Lin-yu TAN Yi-ao YU Jin GUAi-jun XUAN Qiang SUN You-wen |
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| Institution: | SHI Jie-wu,ZHOU Lin-yu,TAN Yi-ao,YU Jin,GU Ai-jun,XUAN Qiang,SUN You-wen Department of Urology,Anhui Provincial Hospital Affiliated To Anhui Medical University,Hefei 230001,P.R.China |
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| Abstract: | OBJECTIVE:To study the role and clinical significance of matrix metalloproteinase-10(MMP-10) and vascular endothelial growth factor(VEGF) in the occurrence and development of renal cell carcinoma.METHODS: The expression of MMP-10 and VEGF were investigated by immunohistochemistry in 56 examples of renal carcinoma tissue,including 20 cases with lymph metastasis and compared the results with those in 10 normal tissues(more than 2 cm away from focus).RESULTS: The expression positive rates for MMP-10 and VEGF i... |
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| Keywords: | kidney neoplasms/pathology carcinoma renal cell/pathology matrix metalloproteinases vascular endothelial growth factor A immunohistochemistry |
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