解酒饮的药理研究及毒性试验

本文研究表明,解酒饮小白鼠最大耐受量>150g/kg/日,相当于成人用量(0.5g/kg/日)的300倍以上;小鼠口服解酒饮10g/kg,5g/kg,可以显著提高酒精中毒的生存率,降低酒精中毒的死亡率,对小鼠肝损坏的保护作用十分显著,使醋氨酚中毒的小鼠生存率达70％,能有效地防止四氯化碳引起的SGPT升高;家兔胃内直接注射解酒饮3.3g/kg,有较强的利尿作用,与对照组相比,有显著性差异(P<0.05)。

PHARMACOLOGICAL STUDY AND TOXICITY TEST ON ANTI-ALCONOLIC BEVERAGE

Through a series of research, it shows that the most tolerance dose of the little mouse drinking anti-alcoho-lic beverage is more than 150g/kg per day, this amount equals to more than 300times of an adult's dosage if mice drink anti-alcoholic beverage 10g/kg, 5g/kg, their alcoholism surviral rate will increase greatly, in another word, their alcoholism deathrate will decrease. It's protective effecf for mouse's hepatic injury is very striking. This method makes the survival rate of mouse's acetaminophen intoxi cation reach 70%.It can also protect SGPT caused by carbon tetrachloride from rising. when Hare is injected anti-alcoholic beverage 3. 3g/kg directly into its stomach, it will produce powerful diuretic effect.Campared with control group, they have great difference, (P<0.05).