Acute exposure to a high-fat diet alters meal patterns and body composition |
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Authors: | Susan J Melhorn Eric G Krause Marie R Mooney Stephen C Woods |
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Institution: | a Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA b Program in Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA c Department of Biomedical Engineering, University of Cincinnati, Cincinnati, OH 45221, USA |
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Abstract: | Weight gain and adiposity are often attributed to the overconsumption of unbalanced, high-fat diets however, the pattern of consumption can also contribute to associated body weight and compositional changes. The present study explored the rapid alterations in meal patterns of normal-weight rats given continuous access to high-fat diet and examined body weight and composition changes compared to chow fed controls. Ten Long-Evans rats were implanted with subcutaneous microchips for meal pattern analysis. Animals were body weight matched and separated into two groups: high-fat or chow fed. Each group was maintained on their assigned diet for nine days and monitored for 22 h each day for meal pattern behavior. Body weight was evaluated every other day, and body composition measures were taken prior and following diet exposure. High-fat fed animals gained more weight and adipose tissue than chow fed controls and displayed a reduced meal frequency and increased meal size. Furthermore, meal size was significantly correlated with the gain of adipose tissue. Together, these results suggest that consumption of a high-fat diet can rapidly alter meal patterns, which in turn contribute to the development of adiposity. |
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Keywords: | Meal patterns High-fat diet Body weight Body composition |
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