| 胃癌患者血清TSGF和IAP测定的临床价值 |
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| 引用本文： | 张红宇,吴昌平,蒋敬庭,邓海峰.胃癌患者血清TSGF和IAP测定的临床价值[J].中国肿瘤临床与康复,2003,10(6):501-502. |
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| 作者姓名： | 张红宇 吴昌平 蒋敬庭 邓海峰 |
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| 作者单位： | 苏州大学附属第三医院肿瘤科,常州,213003 |
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| 摘 要： | 目的探讨胃癌患者血清肿瘤标志物肿瘤特异性生长因子(TSGF)、免疫抑制酸性蛋白(IAP)测定在诊断及化疗疗效评价中的作用。方法用生化比色定量法及单向免疫扩散法分别测定46例胃癌、50例正常对照的TSGF、IAP值。结果 胃癌患者血清TSGF、IAP值较正常对照明显升高,且与胃癌诊断和化疗疗效密切相关。患者中有远处转移者TSGF、IAP测定值较未转移者明显升高。结论检测血清TSGF、IAP对胃癌的早期诊断、评定化疗疗效、监测复发、判断预后有重要的临床意义。
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| 关 键 词： | 胃肿瘤 恶性肿瘤特异性生长因子 免疫抑制酸性蛋白 |
| 文章编号： | 1005-8664(2003)06-0501-02 |
| 修稿时间： | 2002年9月24日 |
Clinical values of serum TSGF and IAP levels in patients with gastric cancer |
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| ZHANG Hong-yu,WU Chang-ping,JIANG Jin-ting,et al.Clinical values of serum TSGF and IAP levels in patients with gastric cancer[J].Chinese Journal of Clinical Oncology and Rehabilitation,2003,10(6):501-502. |
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| Authors: | ZHANG Hong-yu WU Chang-ping JIANG Jin-ting |
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| Abstract: | Objective To investigate the role of tumor markers in the diagnosis and therapeutic efficiency evaluation in patients with gastric cancer.Methods Serum levels of TSGF and 1AP were determined by biochemical colorimetry and SID methods respectively in 46 patients with pathological confirmed gastric cancer and 50 normal subjects. Results The serum levels of TSGF and 1AP in gastric cancer patients were significantly higher than those of normal subjects, and it were related to diagnosis and chemotherapy response of gastric cancer. The levels of advanced carcinoma were higher than those of the early gastric carcinoma. Conclusion The serum TSGF and IAP may contribute to the early diagnosis, chemoresponse evaluation, recurrence monitoring and prognosis evaluation of gastric cancer. |
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| Keywords: | Stomach neoplasm Tumor specific factor Immunosuppressive acidic protein |
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