| 非那雄胺治疗中国男性雄激素性秃发疗效和安全性的临床观察 |
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| 引用本文： | 杨淑霞,季素珍,陈伟,王丹,汪科,王卉,王爱平,韩钢文,刘玲玲,杨海珍,朱学骏. 非那雄胺治疗中国男性雄激素性秃发疗效和安全性的临床观察[J]. 临床皮肤科杂志, 2002, 31(6): 370-372 |
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| 作者姓名： | 杨淑霞 季素珍 陈伟 王丹 汪科 王卉 王爱平 韩钢文 刘玲玲 杨海珍 朱学骏 |
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| 作者单位： | 北京大学第一医院皮肤性病科,北京,100034 |
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| 摘 要： | 通过双盲、随机、安慰剂对照单中心研究，评价非那雄胺治疗中国男性雄激素性秃发的疗效和安全性，结果显示非那雄胺口服1mg/d治疗男性雄激素性秃发的有效率为70．8％，而安慰剂为25．5％，两组比较有显著性差异（P＜0．001），两组中与,奶可能或肯定有关的不良事件发生率无显著性差异，治疗组为0．9％，对照组为1．8％。
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| 关 键 词： | 非那雄胺 中国 男性 雄激素性秃发 疗效 安全性 |
| 文章编号： | 1000-4963(2002)06-0370-03 |
| 修稿时间： | 2002-01-12 |
Clinical study on the efficacy and safety of finasteride for the treatment of androgenetic alopecia in Chinese men |
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| YANG Shu xia,JI Su zhen,CHEN Wei,WANG Dan,WANG Ke,WANG Hui,WANG Ai ping,HAN Gang wen,LIU Ling ling,YANG Hai zhen,ZHU Xue jun. Clinical study on the efficacy and safety of finasteride for the treatment of androgenetic alopecia in Chinese men[J]. Journal of Clinical Dermatology, 2002, 31(6): 370-372 |
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| Authors: | YANG Shu xia JI Su zhen CHEN Wei WANG Dan WANG Ke WANG Hui WANG Ai ping HAN Gang wen LIU Ling ling YANG Hai zhen ZHU Xue jun |
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| Abstract: | In order to evaluate the efficacy and safety of 1mg/day oral finasteride in the treatment of androgenetic alopecia a 24 week double blind,randomized,placebo controlled trial in 228 Chinese men with male pattern hair loss was carried out.The results indicated that the total response rate in finasteride group was 70.8%. However the total response rate in placebo group was 25.5%. There was a statistically significant difference between the two groups (P < 0.001).Adverse effects in both groups were minimal.The incidence of side effects in finasteride group was 0.9%,while in placebo group 1.8%. |
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| Keywords: | finasteride alopecia androgenetic alopecia male pattern |
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