静脉注射6%羟乙基淀粉130/0.4和呋塞米治疗急性胰腺炎的初步研究 |
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引用本文: | 陈康,陈友岱,曾俊,董芸,胡卫建,冯仕彦,刘健,冯卢.静脉注射6%羟乙基淀粉130/0.4和呋塞米治疗急性胰腺炎的初步研究[J].临床合理用药杂志,2009,2(21):5-7. |
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作者姓名: | 陈康 陈友岱 曾俊 董芸 胡卫建 冯仕彦 刘健 冯卢 |
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作者单位: | 四川省医学科学院四川省人民医院急救中心,成都市,610072 |
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摘 要: | 目的观察静脉输注6%羟乙基淀粉130/0.4(万汶)和静脉推注呋塞米(速尿)对急性胰腺炎转归的影响。方法入院当天即给予患者万汶静脉输注(成人通常为1000~2000ml),同时静脉推注呋塞米,力求作到出入量基本平衡;入院第2天开始逐渐减少万汶用量。结果48例急性胰腺炎患者(Ranson评分≥3分者35%,Balthazar CT评分≥D或E者48%),胰腺局部并发症和全身并发症仅为6%和4%,胰腺手术率为4%,1个月病死率为2%。结论静脉输注万汶和静脉推注呋塞米可改善急性胰腺炎的转归。
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关 键 词: | 急性胰腺炎 羟乙基淀粉 呋塞米 |
Preliminary study on the treatment of acute pancreatitis by 6% hydroxyethylstarch 130/0.4 (Voluven) and furosemide |
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Institution: | CHEN Kang, CHEN You-dai, ZENG Jun, et al. (Academy of Medical Sciences, Emergency Center of People's Hospital, Chengdu , Sichuan 610072, China) |
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Abstract: | Objictive To studied the effects on the outcome of acute pancreatitis cases by intravenously administered 6% hydroxyethyl starch 130/0.4 (voluven) and the intravenous injection of furosemide.Methods Patients were given intravenous infusions of voluven (1 000~2 000ml administered for an adult) on the admission day.At the same time,fuorosemide was administered as intravenous bolus,trying to maintain a fluid balance.The amount of voluven administered gradually decreased from the second day.Results 48 patients (35% of patients with a Ranson's score≥3 and 48% with a Balthazar CT ≥ D) were treated with our protocol. Only 6% and 4% patients developed pancreatic and systemic complications respectively, only 4% patients undergone necrosectomy and pseudocyst drainage, and only 2% patients died in one month. Conclusion Our preliminary results suggested that intravenously administered 6% hydroxyethyl starch 130/0.4 solution(voluven) and furosemide might be beneficial for patients with acute pancreatitis. |
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Keywords: | Acute pancreatitis Hydroxyethylstarch solution Furosemide |
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