自拟健脾补肾化瘀汤治疗慢性肾功能不全66例临床观察

目的：观察自拟健脾补肾化瘀汤治疗慢性肾功能不全早、中期患者的临床疗效，为临床早、中期CRF提供有效的方法。方法：将符合纳入标准的66例慢性肾功能不全患者，作为临床观察研究对象。在西医常规治疗的基础上予以中药健脾补’肾化瘀汤口服，治疗结束后，观察治疗前后血肌酐（SCr）、尿素氮（BUN）、内生肌酐清除率（Ccr）、血色素（HB）的变化情况。结果：66例患者治疗前后临床症状均有明显改善，SCr、BUN均有明显下降，Ccr、HB升高。与治疗前比较，差异具有统计学意义（P〈0．05）。结论：健脾补肾化瘀汤治疗早、中期慢性肾衰具有较好的疗效，可有效改善症状、改善’肾功能、改善贫血，中药健脾补肾化瘀法可以保护肾功能，延缓慢性肾衰竭的进程，疗效确切。

Clinical observation on treating 66 cases of chronic renal insufficiency with the Jianpi Bushen Huayu decoction

Objective： To observe clinical efficacy of the Jianpi Bushen Huayu decoction on chronic renal insufficiency in early term and mid-term patients, and to offer effective methods. Methods： 66 cases were selected as research object. All patients were given conventional western treatment plus the Jianpi Bushen Huayu decoction. Change of SCr, BUN, Ccr, HB before and after treatment was observed. Results： Clinical symptoms were improved obviously, SCr and BUN decreased obviously, Ccr and HB increased obviously; the difference was statistically significant （P〈0.05）. Conclusion： The Jianpi Bushen Huayu decoction was confirmed with good efficacy, could inprove symptoms, renal function and anemia, delay chronic renal failure process.