年轻急性心肌梗死患者危险因素及冠脉造影分析

目的 探讨年轻急性心肌梗死(AMI)患者危险因素、冠脉造影特点.方法 对年龄＜45岁AMI患者141例(年轻组)与同期45～64岁AMI患者(中年组)530例进行比较,根据发病高危因素和冠脉造影结果进行对比分析.结果 在年轻组中高血压、糖尿病较少见,而吸烟和冠心病阳性家族史明显高于中年组.年轻组冠脉造影结果以单支病变多见,最常累及LAD,而中年组则以多支病变常见,年轻组住院期间心力衰竭、Ⅲ° AVB及病死率均较低,两组恶性心律失常和室壁瘤差异不明显.结论年轻急性心肌梗死患者中吸烟者较多,糖尿病及高血压病较少见,冠脉病变以单支病变多见,病死率较低.

Risk factors for acute myocardial infarction in young adults and analysis of coronary angiography

Objective To compare and analyze risk factors and coronary angiography of young and older adults with acute myocardial infarction. Methods A total of 141 cases of an initial AMI admitted to our hospital and under 44 years of age( Group Young) were compared to 530 patients over or 45 years, but under 65 years admitted during the same time and because of the same reason( Group Middle) . Results Young adults were found to be predominantly cigarette smoking (82. 0％ vs 51. 1％, P＜0. 01) and had positive family history for coronary artery disease (16. 31％ vs 8. 30％, P=0. 007). Diabetes (17. 73％ vs 26. 06％, P=0. 007) and hypertension (32. 62％ vs 49. 06％, P=0. 001) were less prevalent in the younger group. Coronary angiography was performed in both groups; most of Group Young had single-vessel lesion(54. 7％ vs 39. 0％, P=0. 002), but in Group Middle the right coronary artery and left circumflex coronary artery were most in-volved in. The stroke in hospital of the youngsters was lower (0. 7％ vs 0. 04％, P=0. 04). Conclusion The young patients with AMI have more cigarette smoking and more positive family history for coronary artery disease and single-vessel lesion, but fewer patients have diabetes and hypertension.