Treatment of pure red-cell aplasia following major ABO-mismatched T-cell-depleted bone marrow transplantation |
| |
Authors: | R. Or E. Naparstek N. Mani S. Slavin |
| |
Affiliation: | (1) Department of Bone Marrow Transplantation, Hadassah University Hospital, IL-91120 Jerusalem, Israel;(2) Cancer Immunobiology Research Laboratory, Hadassah University Hospital, IL-91120 Jerusalem, Israel;(3) Blood Bank, Hadassah University Hospital, IL-91120 Jerusalem, Israel |
| |
Abstract: | Major ABO-mismatched bone marrow transplantation (BMT) may be accompanied by red-cell haemolysis, but pure red-cell aplasia following BMT is a rare complication. Two cases of transient pure red-cell aplasia following T-lymphocyte-depleted BMT for a period of >20 weeks are described, both of which responded to one cycle of plasmapheresis. The prompt response of the two patients described with red-cell aplasia with no evidence of haemolysis suggests that plasmapheresis may be considered in such clinical situations as a first treatment of choice before attempting more complex modes of therapy. |
| |
Keywords: | Red blood cell aplasia, in bone marrow transplantation ABO mismatch, in bone marrow tranplantation Bone marrow transplantation ABO mismatch |
本文献已被 SpringerLink 等数据库收录! |
|