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Update on advances in molecular PET in urological oncology
Authors:Kazuhiro Kitajima  Shingo Yamamoto  Kazuhito Fukushima  Ryogo Minamimoto  Takao Kamai  Hossein Jadvar
Institution:1.Department of Radiology, Division of Nuclear Medicine and PET Center,Hyogo College of Medical Center,Nishinomiya,Japan;2.Department of Urology,Hyogo College of Medicine,Nishinomiya,Japan;3.Department of Radiology, Division of Nuclear Medicine,National Center for Global Health and Medicine,Tokyo,Japan;4.Department of Urology,Dokkyo Medical University School of Medicine,Tochigi,Japan;5.Department of Radiology, Division of Nuclear Medicine, Keck School of Medicine,University of Southern California,Los Angeles,USA
Abstract:Integrated positron emission tomography/computed tomography (PET/CT) with 2-18F]fluoro-2-deoxy-d-glucose (18F-FDG) has emerged as a powerful tool for the combined metabolic and anatomic evaluation of many cancers. In urological oncology, however, the use of 18F-FDG has been limited by a generally low tumor uptake, and physiological excretion of FDG through the urinary system. 18F-FDG PET/CT is useful when applied to specific indications in selected patients with urological malignancy. New radiotracers and positron emission tomography/magnetic resonance imaging (PET/MRI) are expected to further improve the performance of PET in uro-oncology.
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