糖尿病家族史与妊娠期糖尿病的相关性

目的:探讨糖尿病家族史与妊娠糖尿病的关系。方法:于2004年12月～2005年9月对天津市区怀孕26～30周孕妇行口服50 g葡萄糖筛查试验,阳性妇女共896人,再行75 g口服葡萄糖耐量试验,发现妊娠糖尿病妇女共367例,并对这些妇女做糖尿病家族史调查。结果:糖尿病家族史是妊娠糖尿病的高危因素,妊娠糖尿病妇女有糖尿病家族史者占31.88%,两代母系(母亲及外祖母)遗传倾向明显大于两代父系(父亲及祖父)。结论:妊娠糖尿病与家族遗传有关,并且妊娠糖尿病的发生具有母系遗传大于父系遗传的倾向。

The relationship between family history of diabetes and gestational diabetes mellitus

Objective: To inquire into the incidence on relationship between gestational diabetes mellitus(GDM) and family history of diabetes.Methods: During Dec.2004~Sep.2005,50g oral glucose screening test(GST) was taken to 26~30 weeks pregnant women in Tianjin,896 of them were positive;OGTT was taken for them,among which,367 person were GDM,and further investigation were made to them on family history of diabetes.Results: Family history of diabetes was the risk factor to GDM.The incident of having family history of diabetes was 31.88% in the women with GDM.It was more influential for the inheritance from mother and grandmother than that from father and grandfather.Conclusion: Family history of diabetes is the risk factor to the GDM,and influence from mother is greater than that from father side.