| 正交设计优化黄白甘草汤的提取工艺 |
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| 引用本文： | 段渠,林俊芝,张定堃. 正交设计优化黄白甘草汤的提取工艺[J]. 辽宁中医杂志, 2014, 0(6): 1246-1248 |
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| 作者姓名： | 段渠 林俊芝 张定堃 |
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| 作者单位： | [1]成都中医药大学附属医院,四川成都610072; [2]成都中医药大学药学院,四川成都611137 |
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| 基金项目： | 四川省教育厅课题（P09304）;国家卫计委课题（lC20130208） |
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| 摘 要： | 目的:优选黄白甘草汤的提取工艺。方法:以多糖、甘草苷、甘草酸含量及干膏率的综合评分为评价指标,通过正交试验考察提取时间、提取次数及溶媒用量对提取工艺的影响。结果:最佳提取工艺为6倍量水提取3次,每次1h。结论:该优选工艺稳定可行,可用于黄白甘草新制剂的制备。
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| 关 键 词： | 黄白甘草汤 正交设计 多糖 甘草苷 甘草酸 |
Optimization of Extraction Process for Huangbai Gancao Decoction by Orthogonal Test |
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| Affiliation: | DUAN Qu, LIN Junzhi, ZHANG Dingkun (1. The Affiliated Hospital of Chengdu University of TCM, Chengdu 610072 ,Sichuan, China; 2. College of Pharmacy, Chengdu University of TCM, Chengdu 611137, Sichuan, China) |
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| Abstract: | Objective： To optimize the extraction process of Huangbai Gancao Decoction. Methods： With composite score of the content of total polyoses,glycyrrhizin,glycyrrhizic acid and dry extract rate as indices,the orthogonal test was applied to optimize the extraction with the extraction time,times and the amount of water as factors. Results： The best extraction conditions were as follows： extracted 3 times with 6-fold the amount of water,1 h each time. Conclusion： This optimized extraction process was reasonable and feasible for preparing new formulation of extraction technology of Huangbai Gancao Decoction. |
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| Keywords: | Huangbai Gancao Decoction orthogonal design total polyoses glycyrrhizin glycyrrhizic acid |
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