| HPLC法测定二羟丙茶碱片中主药的含量 |
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| 引用本文： | 周跃. HPLC法测定二羟丙茶碱片中主药的含量[J]. 中国药房, 2008, 19(7): 542-543 |
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| 作者姓名： | 周跃 |
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| 作者单位： | 新乡医学院第三附属医院,新乡市,453003 |
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| 摘 要： | 目的:建立以高效液相色谱法测定二羟丙茶碱片中主药含量的方法。方法:色谱柱为VP-ODS,流动相为甲醇-水(30∶70),检测波长为273nm,流速为1.0mL·min-1,进样量为20μL。结果:二羟丙茶碱检测浓度的线性范围为8.1~81μg.mL-1(r=0.9998);平均回收率为100.01%,RSD=0.21%。结论:本方法操作简便、准确、精密度好,可用于该制剂的质量控制。
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| 关 键 词： | 高效液相色谱法 二羟丙茶碱片 含量测定 |
| 文章编号： | 1001-0408（2008）07-0542-02 |
| 收稿时间： | 2007-05-17 |
| 修稿时间： | 2007-07-13 |
Determination of Diprophylline in Diprophylline Tablets by HPLC |
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| ZHOU Yue. Determination of Diprophylline in Diprophylline Tablets by HPLC[J]. China Pharmacy, 2008, 19(7): 542-543 |
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| Authors: | ZHOU Yue |
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| Affiliation: | ZHOU Yue(The Third Affiliated Hospital of Xinxiang Medical College, Xinxiang 453003, China) |
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| Abstract: | OBJECTIVE： To establish an HPLC method for the determination of diprophylline in diprophylline tablets. METHODS： The analytical column was C18 and the mobile phase consisted of methanol-water （30-70） at a flow rate of 1.0 mL·min^-1. The detection wavelength was 273 nm and the sample size was 20 μL. RESULTS： The linear range of dipro-phylline was 8.1-81 μg·mL^-1（r=0. 9998） with an average recovery rate of 100.01% （RSD=0.21% ） . CONCLUSION： The method is simple, accurate and precise, and it can be used for the quality control of diprophylline tablets. |
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| Keywords: | HPLC Diprophylline tablet Content determination |
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