同种异体松质骨移植的生物力学研究

目的：探讨同种异体松质骨移植后的力学性能变化以及不同力学环境对其的影响。方法：在40只家兔前肢尺骨中段进行同种异体松质骨移植，并使左右侧植骨块分别承受正常生理载荷与低载荷，动物分批处死后取出植骨区标本进行骨密度值、三点弯曲、平均骨小梁厚度等测试。结果：同种异体松质骨愈合时的骨密度值、最大弯矩、平均骨小梁厚度逐渐上升。在移植后第16周时，和低载荷侧比较，正常载荷侧的上述指标都明显优于低载荷侧（P值分别＜0.01，0.05，0.05）。结论：同种异体松质骨移植后的力学性能变化与它所承受的载荷大小有较强的相关性。

A BIOMECHANICAL STUDY ON THE INCORPORATION OF CANCELLOUS ALLOGRAFT

Objectivet To explore the changes of biomechanical properties of cancellous aIlograft and its relationship with different biomechanical environment. Methodf Cancellous allograft was transplanted to each side of the midshaft diaphyseal ulnar of 40 rabbits. The left transplanted allograft underwent normal physiological load, while the right underwent lower load. Animals were kiIled and specimens taken for examination of bone mineral density, three-point-bending test and mean trabecular thickness. Results: Bone mineral density, maximal bending moment and mean trabecular thickness of graft were found to have been increasing constantly. At the sixteen week after transplantation, the above data of normal loaded graft is better than that of lower loaded graft (P<0.01,0.05,0.05 respectively). Conclusionf Changes of biomechanical properties of cancellous allograft shows more apparent correlation with the magnitude of load to which the graft would be subject.