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Quality of life after endoscopic sinus surgery in refractory pediatric chronic rhinosinusitis
Affiliation:1. Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China;2. Department of Cardiology, Peking University People''s Hospital, No.11, Xi Zhi Men Nan Da Jie, Xicheng District, Beijing 100044, China;3. Department of Cardiology, Second Xiangya Hospital, Central South University, No.139, People Street (M.), Changsha 410011, China;4. Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, No. 6, Tiantan Xi Li, Dongcheng District, Beijing 100050, China;5. MSD China Holding Co., Ltd., No. 1601, Nanjing Rd.(W), JingAn District, Shanghai 20004, China;1. Department of Pediatric Gastroenterology and Nutrition, Emma Children''s Hospital, Academic Medical Center, Amsterdam, The Netherlands;2. Department of Otorhinolaryngology and Head and Neck Surgery, Sophia Children''s Hospital, Erasmus Medical Center, Rotterdam, The Netherlands;3. Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, The Netherlands
Abstract:ObjectiveThe present study aims to evaluate the role of Endoscopic Sinus Surgery (ESS) in refractory pediatric Chronic Rhinosinusitis (CRS) and to assess the change in quality of life after ESS.Materials and MethodsThis prospective interventional study included 35 children (aged between 6 and 12 years) of refractory CRS, not responding to 4 weeks of maximal medical therapy attending the pediatric ENT clinic of a tertiary referral centre. Study period was from November 2013 to March 2016. This patient pool underwent Non Contrast Computed Tomography scan (NCCT) paranasal sinuses and diagnostic nasal endoscopy and those fulfilling the requisite inclusion criteria underwent Endoscopic sinus surgery. Global assessment of Rhinosinusitis Symptom severity score and SN-5 quality of life score of the patients was assessed preoperatively and 1 year after the surgery.Results91.4% children showed an improvement in the total symptom score with a statistically significant (p value < 0.001) reduction in the mean total score postoperatively. Similarly 91.4% of the children showed an improvement in their quality of life with a statistically significant (p value < 0.001) difference seen in the average SN-5 scores after ESS. No major complications were encountered in any of the cases.ConclusionESS is a safe and effective surgical management for children with CRS refractory to maximal medical therapy leading to an improvement in their quality of life.
Keywords:Endoscopic sinus surgery  Pediatric  Chronic rhinosinusitis  Quality of life
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