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细叶远志的化学成分研究
引用本文:汪豪,童玉新,叶文才,赵守训.细叶远志的化学成分研究[J].中国中药杂志,2003,28(9):828-830.
作者姓名:汪豪  童玉新  叶文才  赵守训
作者单位:1. 中国药科大学,天然药物化学教研室,江苏,南京,210038
2. 合肥申联医药科技开发公司,安徽,合肥,230011
摘    要:目的 :对常用传统中药细叶远志Polygala tenuifolia的根进行化学成分研究。 方法 :采用色谱技术进行分离 ,通过1H ,13C NMR等波谱技术确定化合物的结构。结果 :分离并鉴定了 5个化合物 :4-C-β-D-吡喃葡萄糖-1,3 ,6-三羟基-7-甲氧基氧杂蒽酮苷(1) ,4-C-β-D- 呋喃芹菜糖基 (1→6)-β-D-吡喃葡萄糖]-1,3 ,6-三羟基-7-甲氧基氧杂蒽酮苷( 2 ) ,远志皂苷元 ( 3 ) ,远志皂苷元-3-O-β-D-吡喃葡萄糖苷 ( 4 )和 β-胡萝卜苷 (5)。 结论 :其中化合物-1,3 ,4和 5系首次从该植物中分得 ,化合物 1为新的天然产物。

关 键 词:细叶远志  化学成分
文章编号:1001-5302(2003)09-0828-03
收稿时间:2003/2/25 0:00:00
修稿时间:2003年2月25日

Studies on Chemical Constituents in Roots of Polygala tenuifolia
WANG Hao ;TONG Yu-Xin ;YE Wen-Cai ;ZHAO Shou-Xun.Studies on Chemical Constituents in Roots of Polygala tenuifolia[J].China Journal of Chinese Materia Medica,2003,28(9):828-830.
Authors:WANG Hao ;TONG Yu-Xin ;YE Wen-Cai ;ZHAO Shou-Xun
Institution:Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, Jiangsu, China.
Abstract:OBJECTIVE: To study the chemical constituents from the roots of Polygala tenuifolia. METHOD: Column chromatographic techniques were employed for isolation and purification of chemical constituents of the plant and the structures were elucidated by spectroscopic analysis. RESULT: Five chemical constituents were isolated and elucidated as 4-C-beta-glucopyranosyl-1,3,6-trihydroxy-7-methoxyxanthone (1), 4-C-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranosyl]-1,3,6- trihydroxy-7-methoxyxanthone (2), presenegenin (3), presenegenin-3-O-beta-D-glycopyranoside (4) and daucosterol (5), respectively. CONCLUSION: Compounds 1,3,4 and 5 were isolated from this plant for the first time. Compound 1 is a new natural product.
Keywords:chemical constituent  Polygala tenuifolia
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