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利培桐合并氯氮平治疗难治性精神分裂症观察
引用本文:梁绍材,关炳波,等.利培桐合并氯氮平治疗难治性精神分裂症观察[J].山东精神医学,2001,14(1):38-39.
作者姓名:梁绍材  关炳波
作者单位:梁绍材(510370,广州市精神病医院)       关炳波(510370,广州市精神病医院)       余国汉(510370,广州市精神病医院)       文启琴(510370,广州市精神病医院)
摘    要:目的 观察利培酮合并氯氮平治疗难治性精神分裂症的疗效。方法 对32例难治性精神分裂症用利培酮2-6mg/日、氯氮平50-250mg/日治疗共12周,入组前及治疗后2、4、8、12周经BPRS评定。结果 两药合并治疗对难治性精神分裂症有效率为46.88%,治疗中无因明显副反应而停药者。结论 两药合并治疗难治性精神分裂症不失为一种有效的治疗方法。

关 键 词:难治性精神分裂症  利培桐  氯氮平  治疗

Combined treatment of refractory schizophrenia with clozapine and risperidone.
Liang Shaocai,Guan Bingbo,Yu Guohan,et al..Combined treatment of refractory schizophrenia with clozapine and risperidone.[J].Shangdong Archives of Psychiatry,2001,14(1):38-39.
Authors:Liang Shaocai  Guan Bingbo  Yu Guohan  
Institution:Liang Shaocai,Guan Bingbo,Yu Guohan,et al. Guangzhou Psychiatry Hospital,510370
Abstract:Objective To evaluate the efficancy of combining clozapine and risperidone in the treatment of refractory schizophrenia. Methods Thirty two patients with refractory schizophrenia were treated with clozapine 50 - 250mg/d and risperidone 2 - 6mg/d for 12 weeks. All the subjects were assessed with BPRS before and after the treatment.Results Of all the subjects, 46.88% got an satisfactory improvement. The side, effects were minimal. Conclusion Combining clozapine and risperidone is a practical way in the treatment of patients with refractory schizophrenia.
Keywords:Clozapine Risperidone Refractory schizophrenia
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