Abstract: | Summary Electrophoretic motility of hepatic cells and of hepatoma 22 cells was studied after treating these cells with trypsin and disodium ethylene diamine tetra-acetic acid and after changing pH of the medium. As demonstrated, at pH of the medium 7.3 electrophoretic motility of the hepatoma 22 cells is 20% higher than of hepatic cells. Electrophoretic motility of hepatic cells increases in treating them with trypsin and disodium ethylene diamine tetra-acetic acid, as well as with the rise of pH of the medium from 7.3 to 8.0. There was no increase of hepatoma cells motility after the same treatment.A conclusion was drawn that the rise of the negative electric charge of the hepatoma 22 cells (as compared with hepatic cells) was connected with changed capacity to absorb positive ions.Institute of Experimental and Clinical Oncology (Dir.-Active Member of the Akad. Med. Nauk SSSR Prof. N. N. Blokhin)(Presented by Active Member of the Akad. Med. Nauk SSSR L. M. Shabad) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny. Vol. 56, No. 9, pp. 93–95, September, 1963 |