住院精神病病人 2 250例肝炎病毒感染及其影响因素的 logistic回归分析

目的探讨住院精神病病人甲型肝炎病毒( HAV)、乙型肝炎病毒( HBV)、丙型肝炎病毒( HCV)感染发生率，并 logistic回归分析感染影响因素。方法选取新乡医学院第二附属医院 2014年 1月至 2019年 8月 2 250例住院精神病病人作为研究对象。取清晨空腹静脉血检测抗 HAV、HBV、HCV表面抗原，统计 HAV、HBV、HCV感染发生率、感染病人相关指标阳性表达情况，并收集其临床资料，对比不同临床特征病人 HAV、HBV、HCV感染发生率， logistic回归分析病毒性肝炎感染影响因素。结

Logistic regression analysis of hepatitis virus infections in 2 250 cases of psychiatric inpatients and the influencing factors

Objective To investigate the incidences of hepatitis A virus (HAV), hepatitis B virus (HBV), and hepatitis C virus(HCV) infections in hospitalized psychiatric patients, and to analyze the factors influencing the infections using logistic regression.Methods A total of 2 250 inpatients with psychosis hospitalized in Second Affiliated Hospital of Xinxiang Medical College from January 2014 to August 2019 were selected as the study subjects. Early morning fasting venous blood was taken to detect anti-HAV, HBVand HCV surface antigen, and the incidence of HAV, HBV and HCV infection, positive expression of related indexes in infected patients were counted, and their clinical data were collected to compare the incidences of HAV, HBV and HCV infection in patients withdifferent clinical characteristics, and logistic regression was used to analyze the factors influencing viral hepatitis.Results There were 457 viral infections among 2 250 psychiatric inpatients. The incidences of HAV, HBV, and HCV infections were 1.11%, 17.87%, and2.49%, respectively. The proportions of single anti-hepatitis B surface antigen (HBsAg) positivity and single anti-HCV surface antigen positivity were higher than those of single anti-hepatitis A virus-immunoglobulin M (HAV-IgM) positivity, anti-HAV IgM+HBsAg positivity, anti-HAV-IgM+anti-HCV positivity, and HBsAg+anti-HCV positivity. The differences were statistically significant (P < 0.05) in HAV, HBV, and HCV infections in patients with different ages, genders, history of vagrancy, and self-care abilities. Age >20-40 years, female, history of vagrancy, and lack of self-care ability were independent risk factors for viral infections among hospitalized psychiatric patients (P<0.05).Conclusion Psychiatric inpatients are at high risk of HBV infection with some overlapping infections, and the riskof infection is related to age, gender, history of vagrancy, and self-care ability, and preventive and control measures for viral hepatitisamong such patients need to be strengthened on the basis of the actual situation.