| 大强度耐力训练对中枢神经系统的影响 |
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| 引用本文： | 陆阿明,吴金全,孙茂民. 大强度耐力训练对中枢神经系统的影响[J]. 苏州大学学报(自然科学版), 2008, 28(6): 893-896 |
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| 作者姓名： | 陆阿明 吴金全 孙茂民 |
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| 作者单位： | 陆阿明,吴金全,LU A-ming,WU Jin-quan(苏州大学体育学院,江苏苏州,215021);孙茂民,SUN Mao-min(苏州大学医学部,人体解剖学教研室,江苏苏州,215123) |
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| 基金项目： | 教育部高等学校博士学科点专项科研基金，苏州大学211工程建设基金 |
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| 摘 要： | 目的 了解大强度耐力训练对中枢神经系统(CNS)的影响,提出预防CNS损伤的观点.方法 雄性SD大鼠16只,随机分成对照组和大强度耐力训练组.耐力训练6周,训练后取材,采用HE染色、TUNEL法细胞凋亡检测、免疫组化染色及图像分析方法 ,观察12个CNS部位.结果 (1)大强度耐力训练后CNS凋亡细胞的类型主要为神经胶质细胞,长期大强度耐力训练后CNS各部位细胞凋亡百分率显著增加(P<0.01).(2)大强度耐力训练后CNS各部位HSP70表达均显著增加(P<0.01),nNOS表达变化不明显(P>0.05),iNOS的表达均显著增加(P<0.05或<0.01).结论 大强度耐力训练对CNS有一定的损伤,运动训练后须考虑足够的恢复时间.
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| 关 键 词： | 耐力训练 中枢神经系统 损伤 保护 |
Effect of High Intensity Endurance Training on Central Nervous System |
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| LU A-ming,WU Jin-quan,SUN Mao-min. Effect of High Intensity Endurance Training on Central Nervous System[J]. Suzhou University Journal of Medical Science, 2008, 28(6): 893-896 |
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| Authors: | LU A-ming WU Jin-quan SUN Mao-min |
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| Affiliation: | LU A-ming1,WU Jin-quan1,SUN Mao-min2(1.School of P.E.& Sports,Soochow University,Jiangsu Suzhou 215021,China,2.Dept of Anatomy,Medical College of Soochow University,Jiangsu Suzhou 215123,China) |
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| Abstract: | Objective To investigate the effect of high intensity endurance training on central ner-vous system(CNS) and arose the caution to the injury on CNS.Methods Sixteen male SD rats were di-vided into two groups:the control group and high intensity endurance training group.Endurance training lasted for six weeks,HE dyeing,TUNEL and immunohistochemistry technique were applied to observe 12 parts of CNS.Results The type of apoptosis cell in CNS after high intensity endurance training was in the category of glia ce... |
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| Keywords: | endurance training central nervous system injury protection |
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