复方芪麻胶囊治疗气虚痰浊型单纯收缩期高血压病60例临床观察

目的]观察复方芪麻胶囊治疗气虚痰浊型单纯收缩期高血压病(ISH)的临床疗效.方法]选择符合WHO/ISH高血压诊断标准的120例ISH患者,随机分为2组.治疗组60例采用复方芪麻胶囊治疗,对照组60例采用硝苯地平缓释片治疗.2组疗程均为1个月.观察2组的降压疗效和中医证候疗效,比较2组治疗前后血压、24 h动态血压的变化,并评价其安全性和不良反应.结果](1)疗效方面:降压总有效率治疗组为73.3%,对照组为78.4%,2组比较差异无显著性意义(P>0.05);中医证候疗效总有效率治疗组为95.0%,对照组为73.3%,2组比较差异有显著性意义(P<0.05).(2)血压变化方面:治疗后2组收缩压(SBP)较治疗前均明显下降(P<0.05或P<0.01),但治疗后2组间比较差异无显著性意义(P>0.05).治疗后2组的24 h动态血压各项指标均明显改善(与治疗前比较,P<0.05),其中对照组24 h舒张压(DBP)、昼DBP、夜DBP下降幅度更明显(与治疗组比较,P<0.05).(3)安全性和不良反应方面:治疗过程中对照组有3例轻度不良反应,未影响继续治疗.结论]复方芪麻胶囊可以有效降低气虚痰浊型单纯收缩期高血压病患者的收缩压,缩小脉压差,且能明显改善患者的临床症状,是治疗单纯收缩期高血压病的有效中药制剂.

Clinical Observation on Compound Qima Capsules for Treatment of Isolated Systolic Hypertension with Qi Deficiency and Phlegm Turbidity:A Report of 60 Cases

Objective To observe the therapeutic effect of Compound Qima Capsules(CQC) for the treatment of isolated systoljc hypertension(ISH) with Qi deficiency and phlegm turbidity.Methods One hundred and twenty ISH patients subjecting to the diagnostic criteria of WHO/ISH were equally randomized into two groups: the treatment group received CQC and the control group received extended-release Nifedipine Tablets.The treatment course lasted one month.The effect on decreasing hypertension and traditional Chinese medica...