| P-6/ABM复合物促进骨缺损修复的初步实验研究 |
| |
| 引用本文： | 杨旭东,华子春,胡勤刚,黄晓峰. P-6/ABM复合物促进骨缺损修复的初步实验研究[J]. 口腔医学研究, 2004, 20(6): 598-600 |
| |
| 作者姓名： | 杨旭东 华子春 胡勤刚 黄晓峰 |
| |
| 作者单位： | 南京大学医学院附属口腔医院口腔颌面外科,江苏,南京,210008;南京大学医药生物技术国家重点实验室 |
| |
| 摘 要： | 目的：研究细胞结合肽(P-6肽)与无机骨粒(ABM)复合物在骨缺损修复中的作用。方法：将P-6／ABM复合物植入兔颅骨缺损区,分别于2、4、8周进行X线、组织学观察,以ABM植入组为对照,评价其骨修复能力。结果：结果表明X线、组织学检查P-6／ABM组较ABM组有更多新骨形成。结论：P-6／ABM复合材料具有较强的促进骨缺损修复作用。
|
| 关 键 词： | P-6/ABM复合物 骨缺损 修复 |
| 文章编号： | 1671-7651(2004)06-0598-03 |
| 修稿时间： | 2004-07-09 |
Pilot Study on the Repair of bone Defects in Rabbits with the Compound of Cell Binding Peptide and Anorganic Bovine-derived Bone Mineral |
| |
| YANG Xu-dong,HUA Zi-chun,HU Qin-gang,et al.. Pilot Study on the Repair of bone Defects in Rabbits with the Compound of Cell Binding Peptide and Anorganic Bovine-derived Bone Mineral[J]. Journal of Oral Science Research, 2004, 20(6): 598-600 |
| |
| Authors: | YANG Xu-dong HUA Zi-chun HU Qin-gang et al. |
| |
| Affiliation: | YANG Xu-dong,HUA Zi-chun,HU Qin-gang,et al. School of Medicine,Nanjing University,Nanjing 210008 |
| |
| Abstract: | Objective: The purpose of this study is to investigate the effects of the compound of cell binding peptide P-6 and anorganic bovine-derived bone mineral (ABM) in the repair of bone defects. Methods: P-6/ABM and ABM samples were implanted into calvarial defects in rabbits separately. Radiologically and histologically, bone reparative ability was assessed at 2, 4, and 8 weeks postoperation. Results: The bone mass newly formed in P-6/ABM group was significantly more than that in ABM group. Conclusion: The P-6/ABM composite posses the capacity to enhance the bone defect repair in vivo. |
| |
| Keywords: | P-6/ABM Bone defect Repair |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
