Prevalence of severe cardiovascular disease in patients with schizophrenia |
| |
| Affiliation: | 1. Psychiatry and Clinical Psychology Service (G06), Psychotherapeutic Center of Nancy, 1, rue Dr-Archambault, BP 11010, 54521 Laxou cedex, France;2. Department of Evaluation and Medical Informatics, CHRU-Nancy, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54035 Nancy, France;3. Department of Medical Informatics, GHU Paris “Psychiatrie & Neurosciences”, 1, rue Cabanis, 75014 Paris, France;4. Department of Medical Informatics, Ravenel Hospital Center, 1115, avenue René-Porterat, 88500 Mirecourt, France;5. Department of Medical Informatics, Jury Hospital Center, centre hospitalier de Jury, BP 75088, 57073 Metz cedex 3, France;6. Grand Nancy Hospital-university Center for Adult Psychiatry and Addictology, Psychotherapeutic Center of Nancy, 1, rue Dr-Archambault, BP 11010, 54521 Laxou cedex, France;7. University of Lorraine, Lorraine, France;8. Department of Medical Informatics and Clinical Research and Investigation Unit, Psychotherapeutic Center of Nancy, 1, rue Dr-Archambault, 54520 Laxou, France;9. Inserm U1114, France;10. Inserm U1254, France;2. Service de Psychiatrie infanto-juvénile, Hôpital Salvator, Marseille, France;1. School of Medicine, University of Sao Paulo, FMUSP, Sao Paulo (SP), Brazil;2. Eating Disorders Program (AMBULIM/PROTAD), Institute of Psychiatry, FMUSP, R. Dr. Ovídio Pires de Campos, 785 - Cerqueira César, 05403-010 Sao Paulo, SP, Brazil;1. Laboratoire psychologie : dynamiques relationnelles et processus identitaires (Psy-DREPI, EA 7458), département de psychologie, université Bourgogne Franche-Comté, Esplanade Erasme, boulevard du Docteur-Petitjean, 21000 Dijon, France;2. CSAPA La Santoline, SEDAP, Dijon, France;3. Laboratoire de psychologie EA3188, université Bourgogne Franche-Comté, 25000 Besançon, France;1. Pôle hospitalo-universitaire de psychiatrie d’adultes du Grand Nancy, centre psychothérapique de Nancy, 1, rue du Docteur Archambault, 54521 Laxou, France;2. Maison des addictions, CHRU Nancy, Nancy, France;3. Unité de méthodologie, DRCI, BIOBASE, département MPI, data management et statistique UMDS, CHRU-Nancy, 54000 Nancy, France;4. Université de Lorraine, Faculté de Médecine, Département du Grand Est de Recherche en Soins Primaires : DEGERESP, 54000 Nancy, France;5. CNRS, IECL, université de Lorraine, 54000 Nancy, France;6. IADI, U1254, INSERM, Université de Lorraine, CHRU de Nancy Brabois, Nancy, France;7. Inserm U1114, fédération de médecine translationnelle de Strasbourg, département de psychiatrie, centre hospitalier régional universitaire de Strasbourg, 67000 Strasbourg, France |
| |
| Abstract: | ObjectivesWe assessed the prevalence of severe cardiovascular (CV) disease requiring hospitalization among patients with schizophrenia in France.MethodWe included patients hospitalized with schizophrenia or psychotic disorder during 2015, in five French psychiatric hospitals. Patients with CV disease were defined as those with a correspondent ICD-10 code during a hospital stay in any general hospital, five years before or three years after the psychiatric hospitalization. CV disease included myocardial infarction (MI), stroke, heart failure (HF), coronary artery disease (CAD) or peripheral artery disease. Risk factors such as hypertension, obesity and diabetes were recorded.ResultsIn total, 4424 patients with schizophrenia were included. Overall, 203 (4,6%) patients were diagnosed with CV disease, 93 (2.1%) with CAD, 86 (1.9%) with HF and 49 (1.1%) with stroke. The prevalence of hypertension, obesity and diabetes was 11.3%, 9.7% and 7.8%. The median (interquartile range) age of patients with MI and diabetes was 57 (49–70) and 56 (48–66) years.ConclusionPatients with schizophrenia develop severe CV disease requiring hospitalization at an early age. These severe events are associated with a high prevalence of risk factors. Early screening and treatment of CV disease and risk factors is important to improve life expectancy and quality of life of these patients. |
| |
| Keywords: | Schizophrenia Psychotic disorder Cardiovascular disease Cardiovascular risk factors France Schizophrénie Trouble psychotique Maladie cardiovasculaire Facteurs de risque cardiovasculaire France |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
