Loss of Endothelial Cell Matrix Metalloproteinase 14 Reduces Melanoma Growth and Metastasis by Increasing Tumor Vessel Stability |
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| Affiliation: | 1. Department of Dermatology and Venereology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany;2. Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany;1. Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A1STAR), Biopolis, Singapore, Singapore;2. Skin Research Institute of Singapore (SRIS), Agency for Science, Technology and Research (A1STAR), Biopolis, Singapore, Singapore;3. Department of Dermatology, Graduate School of Medicine and Faculty of Medicine, Kyoto University, Kyoto, Japan;4. Department of Biochemistry, Graduate School of Medicine, Juntendo University, Tokyo, Japan;1. Center for Blistering Diseases, European Reference Network-Skin Reference Center (ERN-Skin), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;2. Department of Dermatology, ERN-Skin, Maastricht University Medical Center, Maastricht, The Netherlands;3. GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands;4. Centro de Investigación Biomédica en Red de Enfermedades Raras, Instituto de Salud Carlos III (CIBERER-ISCIII), Madrid, Spain;5. Department of Bioengineering, Universidad Carlos III de Madrid (UC3M), Madrid, Spain;6. Centro de Investigaciones Energéticas Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain;7. Instituto investigación Sanitaria Fundación Jimenez Diaz (IIS-FJD, UAM), Madrid, Spain;8. Division of Dermatology, Department of Medicine, National University Hospital, Singapore, Singapore;9. Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore;10. Department of Dermatology, Hospital Universitario La Paz, Madrid, Spain;11. Tissue Engineering Unit, Centro Comunitario de Sangre y Tejidos del Principado de Asturias, Oviedo, Spain;12. Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Lübeck, Germany;13. Department of Dermatology, University of Lübeck, Lübeck, Germany;1. School of Biomedical Sciences, at the Translational Research Institute, Queensland University of Technology, Brisbane, Australia;2. School of Biomedical Sciences, The University of Queensland, Brisbane, Australia;3. Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA;4. Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA;5. Dermatology Research Centre, The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, Australia;6. The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, Australia;7. Department of Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Herston, Australia;8. Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom;1. Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon, USA;2. Corvallis High School, Corvallis, Oregon, USA;3. Institute for Melanin Chemistry, Fujita Health University, Toyoake, Aichi, Japan;4. Department of Biochemistry and Biophysics, College of Science, Oregon State University, Corvallis, Oregon, USA;5. Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA;6. Department of Dermatology, Oregon Health & Science University, Portland, Oregon, USA;7. OHSU Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA;8. Linus Pauling Institute, Oregon State University, Corvallis, Oregon, USA;1. Skin Barrier Research Group, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic;1. Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA;2. Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA;3. Department of Dermatology, Medical University of Vienna, Vienna, Austria |
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| Abstract: | |
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| Keywords: | BM" },{" #name" :" keyword" ," $" :{" id" :" kwrd0015" }," $$" :[{" #name" :" text" ," _" :" basement membrane EC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0025" }," $$" :[{" #name" :" text" ," _" :" endothelial cell eNOS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0035" }," $$" :[{" #name" :" text" ," _" :" endothelial nitric oxide synthase MMP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0045" }," $$" :[{" #name" :" text" ," _" :" matrix metalloproteinase NO" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" nitric oxide VE-cadherin" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" vascular endothelial–cadherin |
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