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Multi-Trait Genetic Analysis Identifies Autoimmune Loci Associated with Cutaneous Melanoma
Institution:1. Statistical Genetics Lab, QIMR Berghofer Medical Research Institute, Brisbane, Australia;2. Population Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia;3. Experimental Dermatology group, Diamantina Institute, University of Queensland, Brisbane, Australia;4. Faculty of Medicine, The University of Queensland, Brisbane, Australia;5. Leeds Institute of Medical Research at St James’s, Leeds Institute for Data Analytics, School of Medicine, University of Leeds, Leeds, United Kingdom;6. Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA;7. Melanoma Institute Australia, The University of Sydney, Sydney, Australia;8. Faculty of Medicine and Health, The University of Sydney, Sydney, Australia;9. Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital and New South Wales (NSW) Health Pathology, Sydney, Australia;10. Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia;11. Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia;12. Cancer Research UK, Manchester Institute, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom;13. Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom;14. Department of Melanoma, Mater Hospital, North Sydney, Australia;15. Department of Melanoma and Surgical Oncology, Royal Prince Alfred Hospital, Sydney, Australia;16. 23andMe Research Team, 23andMe Inc., Sunnyvale, California, USA;17. Cancer Control Group, QIMR Berghofer Medical Research Institute, Brisbane, Australia;18. Department of Medical Oncology, Mater Hospital, North Sydney, Australia;19. Department of Medical Oncology, Royal North Shore Hospital, St Leonards, Australia;20. Queensland University of Technology (QUT), Brisbane, Australia
Abstract:
Keywords:HWE"}  {"#name":"keyword"  "$":{"id":"kwrd0015"}  "$$":[{"#name":"text"  "_":"Hardy-Weinberg equilibrium  IBD"}  {"#name":"keyword"  "$":{"id":"kwrd0010b"}  "$$":[{"#name":"text"  "_":"identity by descent  KC"}  {"#name":"keyword"  "$":{"id":"kwrd0025"}  "$$":[{"#name":"text"  "_":"keratinocyte cancers  LD"}  {"#name":"keyword"  "$":{"id":"kwrd0035"}  "$$":[{"#name":"text"  "_":"linkage disequilibrium  LDSC"}  {"#name":"keyword"  "$":{"id":"kwrd0045"}  "$$":[{"#name":"text"  "_":"linkage disequilibrium score regression  MAF"}  {"#name":"keyword"  "$":{"id":"kwrd0010x"}  "$$":[{"#name":"text"  "_":"minor allele frequency  MIA"}  {"#name":"keyword"  "$":{"id":"kwrd0055"}  "$$":[{"#name":"text"  "_":"Melanoma Institute Australia  MTAG"}  {"#name":"keyword"  "$":{"id":"kwrd0065"}  "$$":[{"#name":"text"  "_":"multi-trait analysis of GWAS  PC"}  {"#name":"keyword"  "$":{"id":"kwrd0075"}  "$$":[{"#name":"text"  "_":"principal components  RA"}  {"#name":"keyword"  "$":{"id":"kwrd0085"}  "$$":[{"#name":"text"  "_":"rheumatoid arthritis  genetic correlation  UKBB"}  {"#name":"keyword"  "$":{"id":"kwrd0105"}  "$$":[{"#name":"text"  "_":"UK Biobank
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