Cutaneous Transcriptomics Identifies Fibroproliferative and Neurovascular Gene Dysregulation in Prurigo Nodularis Compared with Psoriasis and Atopic Dermatitis |
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| Affiliation: | 1. Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;2. Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA;1. Department of Dermatology, Keio University School of Medicine, Tokyo, Japan;2. Laboratory for Skin Homeostasis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan;1. Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands;2. Department of Dermatology, INSERM U976, Saint-Louis Hospital, University of Paris, Paris, France;3. Department of Dermatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA;4. Cutaneous (Skin) Cancer Treatment Center, Dana-Farber Cancer Institute/Brigham and Women’s Cancer Center, Harvard Medical School, Boston, Massachusetts, USA;1. Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA;2. Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA;3. Institute for Health Services Research in Dermatology and Nursing, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany;4. Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands;5. Janssen Scientific Affairs, LLC, Horsham, Pennsylvania, USA;6. Janssen Research & Development, LLC, Horsham, Pennsylvania, USA;7. Division of Clinical Dermatology & Cutaneous Science, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada;8. Baylor Scott & White Health, Dallas, Texas, USA;9. Department of Dermatology, Weill Cornell Medicine, New York, New York, USA;1. Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;2. Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;3. Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;4. Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;5. Department of Research and Development, Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands;1. Clinical Genetics Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, Maryland, USA;1. Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Florida, USA;2. Monasterium Laboratory, Münster, Germany;3. Jeffrey Cheah Biomedical Centre, Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom;4. The Manchester Centre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom;5. National Institute for Health Research Manchester Biomedical Research Centre, Manchester, United Kingdom |
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| Abstract: | |
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| Keywords: | AD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0015" }," $$" :[{" #name" :" text" ," _" :" atopic dermatitis DEG" },{" #name" :" keyword" ," $" :{" id" :" kwrd0025" }," $$" :[{" #name" :" text" ," _" :" differentially expressed gene GO" },{" #name" :" keyword" ," $" :{" id" :" kwrd0035" }," $$" :[{" #name" :" text" ," _" :" Gene Ontology GSVA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0045" }," $$" :[{" #name" :" text" ," _" :" gene set variation analysis PN" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" prurigo nodularis Th" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" T helper |
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