彩色超声引导联合聚桂醇灌注治疗小儿单纯性肾囊肿 |
| |
引用本文: | 崔西春,范应中,李泸平,刘婷婷,杜昆峰,姚浩宇,王家祥. 彩色超声引导联合聚桂醇灌注治疗小儿单纯性肾囊肿[J]. 中华小儿外科杂志, 2016, 0(4): 282-285. DOI: 10.3760/cma.j.issn.0253-3006.2016.04.010 |
| |
作者姓名: | 崔西春 范应中 李泸平 刘婷婷 杜昆峰 姚浩宇 王家祥 |
| |
作者单位: | 1. 450052,郑州大学第一附属医院小儿外科;2. 450052,郑州大学第一附属医院彩色超声室 |
| |
基金项目: | 2013年河南省医学科技攻关项目(201301004),Medical Science Research Projects of Henan Province in 2013(201301004) |
| |
摘 要: | 目的 探讨彩色超声引导联合聚桂醇灌注治疗小儿单纯性肾囊肿临床疗效,寻找小儿单纯性肾囊肿有效的治疗方法及合适的应用药物.方法 回顾2011年5月至2014年10月我院经彩色超声、CTU明确诊断为单纯性肾囊肿患儿51例,其中28例为聚桂醇治疗组,采用彩色超声引导下经皮穿刺并注入聚桂醇,无水乙醇灌洗法23例设为对照组,对比两组不良反应发生情况及治疗后1年两组疗效情况.结果 51例患儿均穿刺注药成功,治疗后3个月、6个月、1年均获彩色超声随访,聚桂醇治疗组治愈率为85.7%,有效率为92.9%,均高于无水乙醇组的60.9%和65.2%,差异均有统计学意义(P<0.05);聚桂醇治疗组患儿异常哭闹及面红例数均明显较对照组少,差异有统计学意义;聚桂醇治疗组无一例肉眼血尿发生,对照组有6例治疗后出现肉眼血尿,辅助应用止血药物后,均在3d之内消失,差异有统计学意义(P<0.05);聚桂醇治疗组患儿仅1例出现穿刺后发热,对照组治疗后9例出现发热,差异有统计学意义(P<0.05);治疗组患儿穿刺点渗血及呕吐例数均较对照组少,差异均有统计学意义(P<0.05).聚桂醇治疗组二次穿刺例数及手术例数均较无水乙醇组少.结论 彩色超声引导联合聚桂醇灌注治疗小儿单纯性肾囊肿疗效确切、副作用小,应作为小儿单纯性肾囊肿首选治疗方案.
|
关 键 词: | 单纯性肾囊肿 彩色超声 聚桂醇 |
Color ultrasound guidance sclerotherapy with polidocanol for children with simple renal cysts |
| |
Abstract: | Objective To explore the efficacy and safety of color ultrasound guidance sclerotherapy with polidocanol for children with simple renal cysts.Methods A total of 43 children with simple renal cysts were analyzed.The diagnosis was confirmed by computed tomography urography (CTU) and color Doppler ultrasound.Sclerotherapy was performed with ethanol in 23/51cases (45%) and polidocanol in 28/51 (55%).Contrast complications and efficacies were compared after 1 year.Results Color ultrasound guidance sclerotherapy was performed.Follow-ups of color ultrasound were conducted at 3,6 and 12 months respectively.The successful outcome ratio of the polidocanol group was significantly higher than that of the ethanol group (P<0.05).The curative rates were 85.7% vs 60.9% and effective rates 92.9% vs 65.2% respectively.Abnormal crying and facial flushing were less frequent in the polidocanol group than the control group.The polidocanol group had no macroscopic hematuria.In the control group,6 post-therapeutic cases of macroscopic hematuria recovered after a dosing of hemostatic drugs within 3 days.And the difference was statistically significant (P<0.05).Only 1 case of fever was reported in the polidocanol group while 9 cases were feverish in the control group.And the difference was statistically significant (P<0.05).Puncture point errhysis and vomiting were less frequent in the polidocanol group than those in the control group.And the difference had statistical significance (P < 0.05).Conclusions Color ultrasound guidance sclerotherapy with polidocanol is both safe and effective for children simple renal cysts.And it should be a preferred option. |
| |
Keywords: | Simple cyst of kidney Color ultrasound Polidocanol |
本文献已被 万方数据 等数据库收录! |
|