发育性髋关节脱位发病相关因素的研究进展

发育性髋关节脱位(developmental dislocation of the hip,DDH)是小儿骨科常见的疾病、严重危害儿童健康.髋关节发育不良包括髋臼发育不良、髋关节半脱位及全脱位等病理类型.导致该病发病的常见因素包括:阳性家族史、性别、臀位生产、不正确的襁褓方式和母体激素水平等.但是具体病因尚不明确.本文从DDH的发病率、DDH的危险因素、激素对DDH的影响、DDH的易感基因4个方面综述了DDH的研究现状,从而进一步探讨DDH的发病因素.

Pathogenic factors of developmental dislocation of the hip

As a common disease in pediatric orthopedics,developmental dislocation of the hip (DDH) represents a great health hazard for children.Hip dysplasia is composed of acetabular dysplasia and subluxation of hip dislocation.Common pathogenic factors include positive family history,gender,breech delivery,improper nursing care,maternal hormone level and genetic factors,etc.However,specific causes remain undefined.The pathogenesis of DDH is discussed thoroughly from the perspectives of incidence,risk factors,hormonal effects and susceptibility genes.