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脂肪与创面愈合
引用本文:程飚,付小兵,盛志勇. 脂肪与创面愈合[J]. 中国修复重建外科杂志, 2005, 19(1): 78-81
作者姓名:程飚  付小兵  盛志勇
作者单位:1. 广州军区广州总医院整形外科
2. 解放军总医院304临床部,全军创伤修复重点实验室,北京,100037
基金项目:国家重点基础研究发展规划资助项目 (G1 9990 542 0 4 ),国家杰出青年基金资助项目 (3952 50 2 4 ),国家自然科学基金重点项目(30 2 30 370 ),国家自然科学基金资助项目 (30 1 70 966),博士后基金资助项目 (2 0 0 1 .1 4 )~~
摘    要:目的 探讨脂肪组织与创面愈合的关系。方法 通过对近期文献的回顾,脂肪组织参与食物摄入、能量代谢等生理过程。通过内分泌、自分泌和旁分泌参与创面愈合的调节。结果 脂肪组织主要分泌的几种因子:瘦素、细胞因子、生长因子和脂质等参与创面愈合过程。结论 脂肪组织在创面愈合过程中可能具有重要作用,进一步了解脂肪细胞与上皮形成间的关系有助于揭示创面愈合的机制。

关 键 词:创面愈合 脂肪组织 上皮 旁分泌 瘦素 生长因子 细胞因子 生理过程 能量代谢 自分泌
修稿时间:2003-06-03

ADIPOSE TISSUES AND WOUND HEALING
CHENG Biao,FU Xiaobing,SHENG Zhiyong,et al.. ADIPOSE TISSUES AND WOUND HEALING[J]. Chinese journal of reparative and reconstructive surgery, 2005, 19(1): 78-81
Authors:CHENG Biao  FU Xiaobing  SHENG Zhiyong  et al.
Affiliation:The Key Research Laboratory of Wound Repair of PLA, 304th Clinical Department, General Hospital of PLA, Beijing 100037, P R China.
Abstract:Objective To study the relationship between the adipose tissues and cutaneous morphogenesis on wound healing. Methods Adipose tissues' participation in regulation of food intake, energy expenditure, fuel metabolism, and a variety of other physiological processes was reviewed in the latest literature. The wound healing was regulated by endocrine, paracrine, and adipocyte derived molecules. Results Several factors secreted by adipose tissues (leptin, cytokines, growth factors, lipids, metallothioneins, ect) regulated wound healing. Conclusion Adipose tissues may play a vital role in the process of wound healing. Further understanding of the complex interaction between adipose cells and cutaneous morphogenesis is essential to explore the mechanism of wound healing.
Keywords:Adipose Wound healing
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