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四大怀药延缓衰老作用的研究
引用本文:李献平,刘敏,刘世昌,倪允孚,曹凯,李素婷.四大怀药延缓衰老作用的研究[J].中国中西医结合杂志,1991(8):486-487,454.
作者姓名:李献平  刘敏  刘世昌  倪允孚  曹凯  李素婷
作者单位:北京针灸骨伤学院,北京市中医研究所,北京针灸骨伤学院,承德医学院,承德医学院,承德医学院 (北京100015),90级研究生,(北京100015)
摘    要:本实验观察了怀牛膝、怀菊花、怀山药、怀地黄各单味药及四药合剂对小鼠血中超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-Px)活性和过氧化脂质(LPO)的影响。结果表明,"四大怀药"合剂可明显增强鼠血中 SOD 的活性和 GSH-PX 的活力,使 LPO 显著降低。各单味药亦可增强 GSH-Px 的活性,使 LPO 降低。上述结果说明,四大怀药可能具有延缓衰老的作用。

关 键 词:四大怀药  超氧化物歧化酶  过氧化氢酶  谷胱甘肽过氧化物酶  过氧化脂质

Experimental Study on Anti-Senility of the Four Famous Chinese Herbs Produced in Huaiqing Area
Authors:Li Xian-ping
Abstract:The effects of each of the four famous Chinese herbs and the combination of them on the activity of superoxide dismutase (SOD),catalase(CAT),glutathione peroxydase(GSH-Px) and lipid peroxide(LPO)in the blood of young mice were studied.These four famous Chinese herbs produced in Huaiqing area were Radix Achyranthis Bidentatae,Flos Chrysanthemi,Rhizoma Dioscoreae and Radix Rehmanniae.The results indicated that the combination of the four herbs can evidently increas the activity of SOD and GSH-Px,and can apparently reduce LPO in the blood of young mice. Even each of the four herbs alone can increase the activity of GSH-Px and reduce LPO.It is indicated that these four famous Chinese herbs have the effects on anti-senility.
Keywords:four famous Chinese herbs  superoxide dismutase  catalase  glutathione peroxydase  lipid peroxide
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