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大黄炮制前后及大黄配伍芒硝对小鼠胃肠运动的影响
引用本文:李飞艳,张斌,李卫先. 大黄炮制前后及大黄配伍芒硝对小鼠胃肠运动的影响[J]. 中医药导报, 2008, 14(10)
作者姓名:李飞艳  张斌  李卫先
作者单位:湖南中医药高等专科学校,湖南,株洲,412012
摘    要:目的:研究大黄、芒硝对小肠的泻下作用及成分.方法:给小鼠一次性灌胃含活性炭的混悬药液,与含活性炭的生理盐水混悬液相对照,测量胃全重、胃净重、小肠全长、炭末的推进距离,计算出胃残留率及小肠推进率,利用t检验进行统计.结果:与空白组比较,生、熟大黄对胃残留率、小肠推进无明显影响(P>0.05),大黄配芒硝对胃残留率及小肠推进率有显著影响(P<0.05);与熟大黄组比较,生大黄组胃残留率明显降低,大黄配芒硝组胃排空率及肠推进率都明显增大.结论:大黄泻下主要部位不在小肠,结合型蒽醌是主要泻下成分;芒硝对小肠推进作用显著,小肠是其泻下主要部位之一.

关 键 词:大黄  芒硝  胃肠运动

The Influences of Pre and Post Processed Pieplant and Compatibility of Pieplant and Glauber''s Salt on Gastrointestinal Motility of Rat
LI Fei-yan,ZHANG Bin,LI Wei-xian. The Influences of Pre and Post Processed Pieplant and Compatibility of Pieplant and Glauber''s Salt on Gastrointestinal Motility of Rat[J]. GUIDING JOURNAL OF TCM, 2008, 14(10)
Authors:LI Fei-yan  ZHANG Bin  LI Wei-xian
Affiliation:LI Fei-yan,ZHANG Bin,LI Wei-xian Hunan College of Chinese Medicine,Zhuzhou,Hunan,China,412012
Abstract:Objective: To study their purgation to small intestine and ingredients of pieplant and glauber's salt.Methods: Given once intragastric administration with suspension contained absorbite,comparing with normal sodium contained glauber's salt,determining entire and net weight of stomach,total length of small intestine,impelling distance of carbo medicinalis,working out remainning rate of stomach and impelling rate of small intestine.Results: Compared with blank group,crude and prepared pirplant had no effect o...
Keywords:Pieplant  Glauber's salt  Gastrointestinal motility  
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