| 老年黄斑变性血浆过氧化脂质和红细胞超氧化物歧化酶测定的临床意义 |
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| 引用本文： | 陈松,杨锡兰.老年黄斑变性血浆过氧化脂质和红细胞超氧化物歧化酶测定的临床意义[J].眼科研究,1995,13(2):86-88. |
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| 作者姓名： | 陈松 杨锡兰 |
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| 作者单位： | 湖南医科大学附属二院眼科 湖南医科大学附属二院中心实验室(陈松，聂爱光，谭家铨，姜德咏)，( 杨锡兰) |
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| 摘 要： | 对４２例ＡＭＤ和３６例正常对照组血浆过氧化脂质（ＬＰＯ）和红细胞超氧化物歧化酶（ＳＯＤ）活性的测定。结果发现，ＡＭＤ患者血浆ＬＰＯ浓度显著高于，红细胞ＳＯＤ活性显著低于正常对照组（Ｐ〈０．００１）；湿性ＡＭＤ患者血浆ＬＰＯ浓度高于干性ＡＭＤ患者，差异有统计显著性（Ｐ〈０．０５）。揭示ＡＭＤ患者清除自由基（ＦＲ）的能力降低，测定血浆ＬＰＯ和红细胞ＳＯＤ对诊断和治疗ＡＭＤ具有重要意义。
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| 关 键 词： | 黄斑变性 血浆 过氧化脂质 超氧化物歧化酶 诊断 |
Determination of Plasma Liproperoxides and Superoxide Dismutase in
the Red Blood Cells inAging Macular Degeneration and Its Clinical
Signlflcance |
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| Chen Song,et al.Determination of Plasma Liproperoxides and Superoxide Dismutase in
the Red Blood Cells inAging Macular Degeneration and Its Clinical
Signlflcance[J].Chinese Ophthalmic Research,1995,13(2):86-88. |
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| Authors: | Chen Song |
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| Institution: | Chen Song,et alDepartment of Ophthalmology,the
Second Affiliated Hospital,Hospital,Hunan Medical
University,Changsha |
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| Abstract: | lasma liproperoxides ( LPO)and the
activity of superoxide dismutase in the red blood cells (RBC,SOD
)were determined in 42 patients with(AMD)and 36 normal controls.The
results showed that the levels ofLPO is significantly higherand RBC.
SOD was markedly lower in the patients with AMD than that in
normalcontrolsP<0. 001 );the level of LPO in patients with form type
AMD was higher than that in the patientswith dry type AMD.The authors
suggested that the energy of free radical( FR)to be cleared was
decreasedin AMD ,and the determination of the LPO and RBC. SOD is
used for the diagnosis and treatment of AMD. |
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| Keywords: | aging macular degeneration plasma liproperoxides superoxide dismutase diagnosis |
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