| 云芝糖肽对胃癌患者手术及化疗时免疫功能的影响 |
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| 引用本文： | 张洪.云芝糖肽对胃癌患者手术及化疗时免疫功能的影响[J].中国医药导报,2010,7(11):11-12. |
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| 作者姓名： | 张洪 |
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| 作者单位： | 河南省鹤壁市鹤壁煤业集团总医院检验科,河南鹤壁,458000 |
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| 摘 要： | 目的：探讨云芝糖肽对胃癌患者手术及化疗时免疫功能的影响。方法：选择105例胃癌术后及32例胃癌化疗患者,根据是否应用云芝糖肽随机分为单纯手术组、手术合并云芝糖肽组、单纯化疗组及化疗合并云芝糖肽组,分别检测四组红细胞C3b受体花环（RBC-C3bRR）、免疫复合物花环（RBC-ICR）、T细胞亚群以及NK细胞活性。结果：胃癌术后患者中,手术合并云芝糖肽组RBC-C3bRR、CD3、CD4、CD4/CD8、NK细胞活性较单纯手术组显著升高（P〈0.01）,RBC-ICR较单纯手术组显著降低（P〈0.01）;胃癌化疗患者中,化疗合并云芝糖肽组RBC-C3bRR、CD3、CD4、CD4/CD8、NK细胞活性较单纯化疗组显著升高（P〈0.01）,RBC-ICR较单纯化疗组显著降低（P〈0.01）。结论：胃癌患者术后和化疗时合并应用云芝糖肽可明显改善机体的免疫功能。
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| 关 键 词： | 胃癌 红细胞免疫 T细胞亚群 云芝糖肽 |
Effect of polysacchario peptide on the immune function of patients with gastric carcinoma during operation and chemotherapy |
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| ZHANG Hong.Effect of polysacchario peptide on the immune function of patients with gastric carcinoma during operation and chemotherapy[J].China Medical Herald,2010,7(11):11-12. |
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| Authors: | ZHANG Hong |
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| Institution: | ZHANG Hong (Department of Laboratory,Hebi Coal Industry General Hospital of Hebi City,He\'nan Province,Hebi 458000,China) |
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| Abstract: | Objective:To investigate the effect of polysacchario peptide on the immune function of patients with gastric carcinoma during operation and chemotherapy. Methods:105 cases of gastric carcinoma after operation and 32 cases of gastric carcinoma on chemotherapy were selected and randomly divided into simple operation group,operation combined with polysacchario peptide group,simple chemotherapy group and chemotherapy combined with polysacchario peptide group according to using polysacchario peptide or not,the r... |
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| Keywords: | Gastric carcinoma Erythrocyte immune function T-lymphocyte subset Polysacchario peptide |
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