补充维生素D防治多种慢性疾病的研究进展

既往认为维生素D的主要生理功能是维持血钙稳定,而目前的研究发现维生素D具有更多重要作用,如直接作用于肌细胞的维生素D受体,增强肌力,预防跌倒;干预自身免疫系统,防治多发性硬化症、炎症性肠病等自身免疫性疾病;降低多种肿瘤如结直肠癌、乳腺癌等的发生风险。

Current Opinions of Vitamin D Supplementation for Prevention of Chronic Diseases

The main physiological effect of vitamin D has initially been focused on the maintainance of the homeostasis of calcium metabolism.In recent years,more important roles of vitamin D have been identified,which include:it has direct effect on the vitamin D receptor in muscle cells and thus can enhance muscle strength and prevent falls in the elderly patients;it can intervene autoimmune system and prevent and treat autoimmune diseases such as multiple sclerosis and inflammatory bowel disease;and it can decrease...