三种客观评价泪膜的方法探讨

干眼是以泪液质和量以及动力学异常为特征的一种多因素疾病.目前临床上最常使用的评价泪膜的方法为泪膜破裂时间和泪液分泌实验,两种方法均只能获得单一时点数据,主观性强,且具有一定的创伤性.因此,单纯使用上述指标诊断干眼及其亚型对干眼的基础研究和临床诊疗不利.本文总结了目前已经在临床应用的3种无创的、客观的泪膜评价方法,即角膜地形图、波阵面像差和泪膜干涉仪的测量原理和检测指标,比较正常人群和干眼患者之间测量值的差异,为干眼的精确诊断和治疗提供帮助.

Three objective assessments of tear film

Assessing tear film properties is essential for the diagnosis of dry eye. Although tear film break-up time and Schirmer scores have been widely accepted, they are single-value parameters and unable to evaluate the dynamics of tear film in an interblink interval. We reviewed three non-invasive and objective methods, including corneal topography, interferometry and aberrometry. And we also discussed the differences between dry eye patients and normal people detected by these methods.