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多花山竹子茎叶中1个新的缩酚酸环醚化合物
引用本文:崔笛,吉炳琨,黄文忠,王闪闪,李银科,李干鹏,何永辉,蒋孟圆,江志勇,梅双喜,杨志,高雪梅.多花山竹子茎叶中1个新的缩酚酸环醚化合物[J].中草药,2017,48(9):1709-1712.
作者姓名:崔笛  吉炳琨  黄文忠  王闪闪  李银科  李干鹏  何永辉  蒋孟圆  江志勇  梅双喜  杨志  高雪梅
作者单位:云南民族大学民族医药学院 民族药资源化学国家民委教育部重点实验室, 云南 昆明 650500;云南民族大学民族医药学院 民族药资源化学国家民委教育部重点实验室, 云南 昆明 650500;昆明学院 化学科学与技术系, 云南 昆明 650500;云南民族大学民族医药学院 民族药资源化学国家民委教育部重点实验室, 云南 昆明 650500;玉溪师范学院资源环境学院, 云南 玉溪 653100;云南民族大学民族医药学院 民族药资源化学国家民委教育部重点实验室, 云南 昆明 650500;云南民族大学民族医药学院 民族药资源化学国家民委教育部重点实验室, 云南 昆明 650500;云南民族大学民族医药学院 民族药资源化学国家民委教育部重点实验室, 云南 昆明 650500;云南民族大学民族医药学院 民族药资源化学国家民委教育部重点实验室, 云南 昆明 650500;云南白药集团 创新研发中心, 云南 昆明 650500;云南白药集团 创新研发中心, 云南 昆明 650500;云南民族大学民族医药学院 民族药资源化学国家民委教育部重点实验室, 云南 昆明 650500
基金项目:国家自然科学基金资助项目(21562046,21002085,21362044);云南省科技计划项目(2016FB022);云南民族大学研究生创新基金科研项目(2016YJCXS12)
摘    要:目的研究多花山竹子Garcinia multiflora茎叶的化学成分。方法运用硅胶、HPLC等多种色谱技术进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果从多花山竹子茎叶中分离鉴定了1个缩酚酸环醚类化合物,命名为多花山竹子缩酚酸环醚A(1);以及4个酮类化合物,分别鉴定为异巴西红厚壳素(2)、巴西红厚壳素(3)、异爪哇柘酮B(4)、2-二甲基烯丙基-1,3,5-三羟基酮(5)。结论化合物1为新化合物。化合物2~4为已知化合物,化合物2、5为首次从该植物中分离得到。

关 键 词:多花山竹子  缩酚酸环醚类化合物  多花山竹子缩酚酸环醚A  异巴西红厚壳素  2-二甲基烯丙基-1  3  5-三羟基(口山)酮
收稿时间:2016/11/15 0:00:00

A new depsidone from stems-leaves of Garcinia multiflora
CUI Di,JI Bing-kun,HUANG Wen-zhong,WANG Shan-shan,LI Yin-ke,LI Gan-peng,HE Yong-hui,JIANG Meng-yuan,JIANG Zhi-yong,MEI Shuang-xi,YANG Zhi and GAO Xue-mei.A new depsidone from stems-leaves of Garcinia multiflora[J].Chinese Traditional and Herbal Drugs,2017,48(9):1709-1712.
Authors:CUI Di  JI Bing-kun  HUANG Wen-zhong  WANG Shan-shan  LI Yin-ke  LI Gan-peng  HE Yong-hui  JIANG Meng-yuan  JIANG Zhi-yong  MEI Shuang-xi  YANG Zhi and GAO Xue-mei
Institution:Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Kunming 650500, China;Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Kunming 650500, China;Department of Chemical Science and Technology, Kunming University, Kunming 650500, China;Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Kunming 650500, China;College of Resource and Environment, Yuxi Normal University, Yuxi 653100, China;Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Kunming 650500, China;Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Kunming 650500, China;Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Kunming 650500, China;Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Kunming 650500, China;Innovation and R & D Center, Yunnan Bai Yao Group, Kunming 650500, China;Innovation and R & D Center, Yunnan Bai Yao Group, Kunming 650500, China;Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Kunming 650500, China
Abstract:Objective To study the chemical constituents in stems-leaves of Garcinia multiflora. Methods The chemical constituents from stems-leaves of G.multiflora were isolated by silica gel and HPLC methods. Their structures were elucidated by spectroscopic methods and physicochemical properties. Results One new depsidone isolated from stems-leaves of G.multiflora was named as multidepsidone A (1), and four xanthones isolated from stems-leaves of G.multiflora were identified as isojacareubin (2), jacareubin (3), isocudraniaxanthone B (4), and 2-dimethylallyl-1,3,5-trihydroxyxanthone (5). Conclusion Compound 1 is a new compound. compounds 2-4 are known compounds, and compounds 2 and 5 are obtained from this plant for the first time.
Keywords:Garcinia multiflora Champ  ex Benth  depsidone  multidepsidone A  isojacareubin  2-dimethylallyl-1  3  5-trihydroxyxanthone
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