| 恶性胶质瘤的放射免疫治疗 |
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| 引用本文： | 高云朝. 恶性胶质瘤的放射免疫治疗[J]. 国际放射医学核医学杂志, 2004, 28(4): 149-152 |
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| 作者姓名： | 高云朝 |
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| 作者单位： | 200040 上海, 复旦大学附属华山医院核医学科 |
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| 摘 要： | 恶性胶质瘤以手术切除为主,辅以放疗和化疗,在此基础上再进行适当的放射免疫治疗,可进一步延长生存期。131I和90Y标记的抗腱生蛋白抗体用于恶性胶质瘤的实验和临床Ⅰ、Ⅱ期治疗研究获得了满意效果。
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| 关 键 词： | 胶质瘤 放射免疫治疗 抗腱生蛋白单抗 |
| 文章编号： | 1001-098X(2004)04-0149-04 |
| 收稿时间： | 2003-11-01 |
| 修稿时间： | 2003-11-01 |
Radioimmunotherapy for malignant glioma |
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| GAO Yun-chao. Radioimmunotherapy for malignant glioma[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2004, 28(4): 149-152 |
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| Authors: | GAO Yun-chao |
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| Affiliation: | Department of Nuclear Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China |
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| Abstract: | Malignant glioma is treated mainly by surgery with chemotherapy and external radiothera-py as adjuvant remedies. Survival time can be prolonged if appropriate radioimmunotherapy is employed as another concurrent alternative. Per-clinical, clinical phase I and II studies of 131I and 90Y labeled anti- tenascin monoclonal antibodies in the treatment of malignant glioma have resulted in satisfactory therapeu-tic efficacy. |
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| Keywords: | glioma radioimmunotherapy anti-tenascin monoclonal antibodies |
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