|
|||||
|
|
Immunomodulatory drugs (IMiDs) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kappaB, OCT-1, or NF-AT. |
|
| Authors: | Faribourz Payvandi Lei Wu Syedah D Naziruddin Maura Haley Anastasia Parton Peter H Schafer Roger S Chen George W Muller Christopher C W Hughes David I Stirling |
| Institution: | Department of Immunotherapeutics, Celgene Corporation, Summit, NJ 07901, USA. fpayvandi@celgene.com |
| Abstract: | |
| Keywords: | |