阶段性干预对复发性抑郁症患者生活质量的影响

目的探讨阶段性护理干预对复发性抑郁症患者生活质量、服药依从性及复发的影响。方法将96例复发性抑郁症患者随机分为观察组和对照组各48例。两组均予以氟西汀系统治疗,对照组行常规护理;观察组在此基础上分阶段实施护理干预,时间为8周,随后进行为期2年的随访。采用生活质量量表(QOL-100)分别于治疗前及随访结束时进行评估,并于随访6个月、1年、2年时了解两组患者的服药依从性、复发率及再住院情况。结果随访结束时,两组患者的生活质量均有所改善(P<0.05,P<0.01),但观察组患者的生活质量总评、心理领域、独立性领域及社会关系领域评分显著优于对照组(P<0.05,P<0.01)。观察组复发率及再住院率分别为10.42%和6.25%,均明显低于对照组的33.3%和27.1%(P<0.05,P<0.01);而服药依从性显著高于对照组(P<0.05,P<0.01)。结论分阶段实施护理干预有助于改善复发性抑郁症患者的生活质量,提高服药依从性,降低复发及再住院率。

Effect of Stage-based Intervention on Quality of Life in Patients with Recurrent Depression

Objective To explore the effect of stage-based intervention on quality of life,medication compliance and recurrence in patients with recurrent depression.Methods Ninety-six patients with recurrent depression were divided into observation group(n=48,treated with general intervention in combination with fluoxetine for 8 weeks) and control group(n=48,treated with fluoxetine for 8 weeks).Both groups were followed-up for 2 years.Patients were (evaluated) with QOL-100 before treatment and at the end of follow-up.At 6 months,1 and 2 years after follow-up,rates of recurrence and readmission as well as medication compliance were investigated.Results The QOL of both groups were improved(P<0.05,P<0.01).But the total score of QOL,scores of psychology,independence and social ralationship in the observation group were significantly higher than those in the control group at the end of follow-up(P<0.05,(P<)0.01).At the end of follow-up,the rates of recurrence and readmission were 10.42% and 6.25% respectively in the observation group,significantly lower than those in the control group(P<0.05,P<0.01).In the observation group,medication compliance was higher than that in the control group(P<0.05,P<0.01).Conclusion Stage-based intervention could improve the QOL,increase medication compliance and decrease the recurrent rate of patients with recurrent depresion.