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84例糖尿病伴大肠埃希菌尿路感染药敏分析
引用本文:韦玉和,赵志勇,罗春媛.84例糖尿病伴大肠埃希菌尿路感染药敏分析[J].医学综述,2008,14(18):2863-2865.
作者姓名:韦玉和  赵志勇  罗春媛
作者单位:江苏大学附属武进医院内分泌科,江苏,常州,213002
摘    要:目的回顾性分析糖尿病伴大肠埃希菌尿路感染病例药敏试验结果,以指导临床合理选择抗生素。方法取糖尿病伴尿路感染的患者清洁中段尿进行培养,用法国梅里埃自动鉴定仪进行细菌鉴定及药敏试验;按年份、超广谱β-内酰胺酶(ESBLs)等分组分析。结果在165份尿培养阳性标本中检出大肠埃希菌占50.9%(84/165),大肠埃希菌ESBLs阳性率41.7%(35/84),ESBLs阳性菌株对多种常用抗菌素的耐药率高于ESBLs阴性菌株,所有菌株均对亚胺培南、美罗培南敏感;ESBLs阳性组有3例合并肠球菌感染,其中1例万古霉素耐药;近期组较早期组ESBLs阳性率明显升高、耐药状况更严重。结论糖尿病伴大肠埃希菌尿路感染应根据药敏试验结果合理使用抗生素,亚胺培南、美罗培南为敏感药物。

关 键 词:糖尿病  尿路感染  大肠埃希菌  药敏试验

Analysis of Drug Sensitivity Test of Escherichia Coli in Urinary Tract Infection in 84 Patients with Diabetes Mellitus
WEI Yu-he,ZHAO Zhi-yong,LUO Chun-yuan.Analysis of Drug Sensitivity Test of Escherichia Coli in Urinary Tract Infection in 84 Patients with Diabetes Mellitus[J].Medical Recapitulate,2008,14(18):2863-2865.
Authors:WEI Yu-he  ZHAO Zhi-yong  LUO Chun-yuan
Institution:WEI Yu-he,ZHAO Zhi-yong,LUO Chun-yuan.(Department of Endocrinology,Affiliated Wujin Hospital,Jiangsu University,Changzhou 213002,China)
Abstract:Objective To analyze the drug-resistance of Escherichia Coli in patients with diabetes mellitus and urinary tract infection,and to provide scientific evidence for rational use of antibiotics.MethodsUrinary samples were collected from patients with diabetes mellitus and urinary tract infection.They were cultivated and analyzed by drug sensitivity test and ESBLs test.ResultsThe detection rate of Escherichia Coli was 50.9%(84/165)in urinary samples,The detection rates of ESBLs was 41.7%(35/84)in Escherichia Co...
Keywords:Diabetes mellitus  Urinary tract infection  Escherichia coli  Drug sensitivity test  
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