| 鼻咽癌侵犯颅底的CT表现及其与预后的关系 |
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| 引用本文： | 姚雪松,罗德红,赵燕风,李二妮,王小艺,李琳,王振常,周纯武. 鼻咽癌侵犯颅底的CT表现及其与预后的关系[J]. 当代医学, 2009, 15(20): 31-34 |
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| 作者姓名： | 姚雪松 罗德红 赵燕风 李二妮 王小艺 李琳 王振常 周纯武 |
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| 作者单位： | 1. 中国医学科学院北京协和医学院肿瘤医院影像诊断科,100021,北京
2. 首都医科大学附属北京同仁医院放射科,100730,北京 |
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| 摘 要： | 目的分析鼻咽癌侵犯颅底的CT表现，探讨颅底不同结构受侵与病变预后的关系。方法回顾性分析本院667例经病理证实的鼻咽癌患者首次CT检查表现及临床资料，采用Kaplan-Meier行生存分析．Log—rank检验颅底不同结构受侵的无远处转移生存率（freedom from distant metastasis，FDM）差异有无显著性。结果667例鼻咽癌侵犯颅底240例（360％），未侵犯颅底427例（640％）。颅底有无受侵，对于患者无远处转移生存率影响的差异，统计学意义有非常显著性（P=0.000），其中翼突、岩枕缝、翼管、蝶窦有无受侵的差异，统计学意义有非常显著性（P值分别为0.002、0.006、0.003、0.005）．斜坡、破裂孔、海绵窦差异的统计学意义有显著性（P值分别为0.032、0.025、0.049），环椎、卵圆孔、棘孔、圆孔、眶下裂、颈静脉孔、眶上裂差异无统计学意义（P值分别为0.129、0.065、0.066、0.059、0.074、0.177、0.786）。岩枕缝、卵圆孔、棘孔、翼管、破裂孔、圆孔、海绵窦、眶下裂单侧受侵、双侧受侵对无远处转移生存率影响差异无统计学意义（P值分别为0.688、0.200、0.383、0．583、0.590、0.876、0.932、0．188）。颅底骨质破坏CT表现可分为溶骨性骨质破坏、骨质增生硬化、破坏与硬化兼有三种类型。蝶窦、翼突、斜坡骨质破坏三种类型对无远处转移生存率影响差异无统计学意义（P值分别为0．448、0.387、0.056）。结论鼻咽癌患者CT检查，详细分析颅底有无受侵及不同结构受侵情况，对于评价病变预后有重要意义。
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| 关 键 词： | 鼻咽癌 颅底 体层摄影术, X线计算机 预后 |
CT Appearances of Skull Base Erosion in Nasopharyngeal Carcinoma and its Correlation with Prognosis |
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| Xue-song YAO,De-hong LUO,Yan-feng ZHAO,Er-ni LI,Xiao-yi WANG,Lin LI,Zhen-chang WANG,Chun-wu ZHOU. CT Appearances of Skull Base Erosion in Nasopharyngeal Carcinoma and its Correlation with Prognosis[J]. Contemporary Medicine, 2009, 15(20): 31-34 |
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| Authors: | Xue-song YAO De-hong LUO Yan-feng ZHAO Er-ni LI Xiao-yi WANG Lin LI Zhen-chang WANG Chun-wu ZHOU |
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| Affiliation: | Xue-song YAO1,De-hong LUO1,Yan-feng ZHAO1,Er-ni LI1,Xiao-yi WANG1,Lin LI1,Zhen-chang WANG2,Chun-wu ZHOU11.Department of Diagnostic Imaging,Cancer Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100021,China 2.Department of Radiology,Beijing Tongren Hospital affiliated to Capital University of Medical Sciences,Beijing 100730,China |
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| Abstract: | Objective To study CT appearances of skull base erosion,analyze the correlation between different structure erosion and prognosis in nasopharyngeal carcinoma(NPC). Methods Primarily CT appearances and clinical files of 667 NPC patients proved by pathology were reviewed. Overall survival was analyzed using the Kaplan-Meier method. Difference between skull base structures was analyzed using the Log-rank test. Results 667 NPC patients included 240 patients with skull base erosion(36.0%) and 427 patients withou... |
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| Keywords: | Nasopharyngeal carcinoma Skull base Tomography X-ray computed Prognosis |
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