2012—2018年重庆市脑出血与脑梗死疾病负担变化趋势

目的 了解2012—2018年重庆市脑出血与脑梗死疾病负担变化趋势,为开展有针对性的干预措施提供建议。方法 2012—2018年重庆市脑卒中个案资料来源于中国疾病预防控制中心国家心脑血管事件登记报告系统,计算脑卒中、脑出血、脑梗死发病率、标化发病率、死亡率、标化死亡率、伤残调整生命年（DALY）、早逝所致寿命损失年（YLL）和伤残所致寿命损失年（YLD）。率的趋势变化采用年度变化百分比（APC）,并对APC进行t检验。结果 重庆市脑卒中、脑出血、脑梗死YLD率分别由2012年的3.37‰、0.91‰、2.46‰上升至2018年的4.03‰、1.01‰、2.64‰,APC分别为3.67%、4.39%、1.61%,脑卒中YLD率变化趋势有统计学意义（P<0.01）。脑卒中、脑出血、脑梗死YLL率分别由2012年的18.38‰、11.61‰、3.29‰上升至2018年的20.10‰、12.01‰、5.40‰,APC分别为1.01%、0.40%、7.68%,脑梗死YLL率变化趋势有统计学意义（P<0.01）。脑卒中、脑出血、脑梗死DALY率分别由2012年的21.75‰、12.52‰、5.75‰上升至2018年的24.13‰、13.02‰、8.04‰,APC分别为1.51%、0.70%、5.34%,脑梗死DALY率变化趋势有统计学意义（P<0.01）。结论 重庆市脑卒中DALY率低于全国平均水平,脑出血DALY率贡献率超过50%,脑梗死疾病负担呈上升趋势,应重视脑卒中防治,预防脑梗死发病率的快速上升,提高脑出血的救治水平。

Trend of disease burden of cerebral hemorrhage and cerebral infarction in Chongqing,2012-2018

Objective To understand the trend of disease burden of cerebral hemorrhage and cerebral infarction from 2012 to 2018 in Chongqing,and provide the suggestion for conducting the pertinent intervention.Methods The data of stroke cases in Chongqing from 2012 to 2018 were from the National System for Registering and Reporting Cardiovascular and Cerebrovascular Events of Chinese Center for Disease Control and Prevention.The incidence,standardized morbidity,mortality,standardized mortality,disability adjusted life years(DALY),years of life lost(YLL)and years lived with disability(YLD)were calculated for stroke,cerebral hemorrhage and cerebral infarction.The change trend of rate was indicated by annual percentage change(APC),and the t-test was carried out on APC.Results The rate of YLD of stroke,cerebral hemorrhage and cerebral infarction increased from 3.37‰,0.91‰,2.46‰in 2012 to 4.03‰,1.01‰,2.64‰in 2018 respectively.And its APC was 3.67%,4.39%and 1.61%respectively.The change trend of YLD of stroke was statistically significant(P<0.01).The rate of YLL of stroke,cerebral hemorrhage and cerebral infarction increased from 18.38‰,11.61‰,3.29‰in 2012 to 20.10‰,12.01‰,5.40‰in 2018 respectively.And its APC was 1.01%,0.40%and 7.68%respectively.The change trend of YLL of cerebral infarction was statistically significant(P<0.01).The rate of DALY of stroke,cerebral hemorrhage and cerebral infarction increased from 21.75‰,12.52‰,5.75‰in 2012 to24.13‰,13.02‰,8.04‰in 2018 respectively.And its APC was 1.51%,0.70%and 5.34%respectively.The change trend of DALY of cerebral infraction was statistically significant(P<0.01).Conclusion The rate of DALY of stroke in Chongqing was lower than national average level.The proportion of cerebral hemorrhage was over 50%of all stroke.The disease burden of cerebral infraction increased year by year in Chongqing.It should be attached importance on stroke control and prevention to curb the rapid increasing of cerebral infarction and raise the capability for cerebral hemorrhage.