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Tics in a patient with Parkinson's disease |
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| Authors: | H Shale S Fahn R Mayeux |
| Affiliation: | Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York 10032. |
| Abstract: | A patient with Gilles de la Tourette syndrome later developed Parkinson's disease in middle age. This was accompanied by a marked reduction in the frequency of tics but levodopa toxicity exacerbated the tics. The dopamine hypothesis of tic disorders is supported by this observation. |
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